Effects of increasing insulin secretion on acute postexercise blood glucose disposal

Medicine and Science in Sports and Exercise
Brechje KaastraLuc J C Van Loon

Abstract

Coingestion of protein and/or free amino acids with carbohydrate has been reported to accelerate postexercise muscle glycogen synthesis due to an increase in the insulin response. To determine the extent to which the combined ingestion of carbohydrate and a casein protein hydrolysate with or without additional free leucine can increase insulin levels during postexercise recovery in endurance-trained athletes. To determine how this affects whole-body plasma glucose disposal during postexercise recovery. Fourteen male athletes (age: 24.3 +/- 0.8 yr; VO2max: 62.9 +/- 1.4 mL.kg.min) were subjected to three randomized crossover trials in which they performed 2 h of exercise (55% Wmax). Thereafter, subjects were studied for 3.5 h during which they ingested carbohydrate (CHO: 0.8 g.kg.h), carbohydrate and a protein hydrolysate (CHO-PRO: 0.8 and 0.4 g.kg.h, respectively), or carbohydrate, a protein hydrolysate, and free leucine (CHO-PRO-LEU: 0.8, 0.4, and 0.1 g.kg.h, respectively) in a double-blind fashion. Continuous infusions with [6,6-H2] glucose were applied to quantify plasma glucose appearance (Ra) and disappearance rates (Rd). Plasma insulin responses were 108 +/- 17 and 190 +/- 33% greater in the CHO-PRO and CHO-PRO-LEU trial, ...Continue Reading

References

Jan 1, 1991·Medicine and Science in Sports and Exercise·J J ZachwiejaW J Fink
Feb 1, 1989·Journal of Applied Physiology·M J ReedJ L Ivy
Nov 1, 1988·Journal of Applied Physiology·J L IvyM J Reed
Oct 1, 1967·Acta Physiologica Scandinavica·J BergströmB Saltin
Jun 1, 1995·Journal of Applied Physiology·L M BurkeM Hargreaves
Jan 1, 1994·Journal of Applied Physiology·T B PriceR G Shulman
Apr 1, 1993·Journal of Applied Physiology·J A DoyleR L Strauss
Feb 22, 2000·International Journal of Sports Medicine·G van HallA J Wagenmakers
Jun 29, 2000·The American Journal of Clinical Nutrition·L J van LoonA J Wagenmakers
Sep 18, 2002·Journal of Applied Physiology·John L IvyThomas B Price
Mar 6, 2003·Sports Medicine·Roy Jentjens, Asker Jeukendrup
Oct 7, 2004·Journal of the American College of Nutrition·Thomas L Halton, Frank B Hu

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Citations

Jun 4, 2013·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Andrew H HallCecilia M Shing
Oct 28, 2011·Nutrition Reviews·Marika Leenders, Luc J C van Loon
May 16, 2009·Journal of the International Society of Sports Nutrition·Lynne KammerJohn L Ivy
Nov 24, 2011·Journal of the International Society of Sports Nutrition·Tsong-Rong JangChen-Kang Chang
Oct 23, 2013·Journal of the International Society of Sports Nutrition·Louise DeldicquePeter Hespel
Apr 29, 2008·Ultrasound in Medicine & Biology·Marcelo R GuerinoEliete Luciano
Apr 15, 2008·Medicine and Science in Sports and Exercise·James A BettsKostas Tsintzas
Jul 9, 2008·Current Sports Medicine Reports·Melinda Millard-StaffordJill A Rahnert
Jul 8, 2020·Nutrients·Shawn M ArentMichelle A Arent

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