PMID: 8613607Mar 15, 1996Paper

Effects of intraaortic balloon pumping on septal arterial blood flow velocity waveform during severe left main coronary artery stenosis

Journal of the American College of Cardiology
A KimuraF Kajiya

Abstract

We sought to evaluate the effect of intraaortic balloon pumping on the phasic blood velocity waveform into myocardium with severe coronary artery stenosis. In the presence of severe coronary artery stenosis, it is not clear whether intraaortic balloon pumping augments intramyocardial inflow during diastole or changes systolic retrograde blood flow from the myocardium to the extramural coronary arteries. Using anesthetized open chest dogs (n=7), we introduced severe stenosis in the left main coronary artery to reduce the poststenotic pressure to approximately 60 mm Hg (>90% diameter stenosis). Septal arterial blood flow velocities were measured with a 20-MHz, 80-channel ultrasound pulsed Doppler velocimeter. Left anterior descending arterial flow, aortic pressure and poststenotic distal coronary pressure were measured simultaneously. The diastolic anterograde flow integral and systolic retrograde flow integral were compared in the presence and absence of intraaortic balloon pumping. Although intraaortic balloon pumping augmented diastolic aortic pressure, this pressure increase was not effectively transmitted through stenosis. Septal arterial diastolic flow velocity was not augmented, and left anterior descending arterial flow w...Continue Reading

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Citations

Mar 15, 1996·Journal of the American College of Cardiology·D O Williams
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Sep 10, 2013·European Heart Journal·Karl WerdanJudith S Hochman
Feb 24, 2015·JACC. Cardiovascular Interventions·Aung MyatDeepak L Bhatt
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Aug 3, 2001·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·M TakagakiK Fukamachi
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