Abstract
The present study reports on the late effects of increasing doses of radiation on the biomechanics of commercially pure titanium implants (fixtures) installed in the proximal tibia in 26 rats. Twelve weeks after various doses (10, 20, 30, and 35 Gy) of irradiation, the fixtures were inserted into rat tibiae, and after another eight weeks these were tested mechanically in vivo. Acute dose dependent skin reactions developed after all doses except 10 Gy, but most subsided within two to three weeks. There was a statistically significant reduction in torsion but the pull-out load was not significantly reduced for single doses up to 30 Gy. Histological analysis showed that bone remodelling was impaired. Shear stresses and shear moduli were estimated for the bone-implant interface and in the surrounding bone tissue. These estimated stresses and moduli were not found to be correlated to the dose of radiation.
References
Feb 1, 1976·Cancer·R G Parker, H C Berry
Jul 1, 1991·Clinical Oral Implants Research·L SennerbyP Astrand
May 1, 1987·Hypertension·M D Thames
Nov 1, 1985·International Journal of Radiation Oncology, Biology, Physics·M JacobssonI Turesson
Jan 1, 1966·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·A Sams
Jan 1, 1970·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·N F Kember, M Sadek
Aug 1, 1982·Journal of Oral Pathology·K Donath, G Breuner
May 1, 1995·Seminars in Surgical Oncology·J BeumerR Nishimura
Jun 1, 1995·The Journal of Bone and Joint Surgery. American Volume·T A Einhorn
Apr 1, 1993·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·G GranströmJ Fornander
Jul 1, 1997·Biomaterials·R BrånemarkP Thomsen
Nov 1, 1953·Acta Radiologica·G KOK
Nov 1, 1957·The American Journal of Anatomy·J S ARNOLD, W S JEE
Jan 1, 1960·Acta Orthopaedica Scandinavica·A HULTH, O WESTERBORN
Jul 1, 1963·The British Journal of Radiology·J BLACKBURN, A B WELLS
Apr 1, 1965·The British Journal of Radiology·J P BENSTED, V D COURTENAY
Apr 1, 1962·The British Journal of Radiology·S MACPHERSONJ VAUGHAN
Citations
Jul 1, 1997·Biomaterials·R BrånemarkP Thomsen
Nov 6, 2014·Photomedicine and Laser Surgery·Meire Maman Fracher AbramoffLydia Masako Ferreira
Aug 30, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Stefan IhdeV S Konstantinović
Apr 16, 2011·Clinical Oral Implants Research·João Augusto Guedes de OliveiraAna Paula Rosifini Alves Claro
May 2, 2012·Journal of Clinical Periodontology·Daniel S ThomaRonald E Jung
Feb 19, 2013·Clinical Oral Implants Research·Jun Yuan LiLim Kwong Cheung
Oct 23, 2012·Free Radical Biology & Medicine·Tapasi RanaSwati Biswas
May 26, 2010·Acta Cirúrgica Brasileira·Emne Hammoud GumieiroLuciano Lauria Dib
Nov 2, 2011·Acta Cirúrgica Brasileira·Susette Cavicchioli LucattoRonaldo Antonio Leite
Sep 6, 2014·Implant Dentistry·Roberta Targa Stramandinoli-ZanicottiAndré Lopes Carvalho
Feb 1, 2012·The Journal of International Medical Research·C DemirelA Yildiz
Jan 6, 2001·Journal of Dental Research·T OgawaI Nishimura
Mar 16, 2011·The Journal of Craniofacial Surgery·Gilberto SammartinoCarmen Mortellaro
Jun 20, 2019·Head & Neck·Phillip MooreIan Hewson
Aug 23, 2019·Medicina·Dheyauldeen ShabeebMasoud Najafi
Jun 4, 2019·Clinical Oral Investigations·Mariana Raquel da Cruz VegianLuana Marotta Reis de Vasconcellos
Sep 3, 2003·Periodontology 2000·Gösta Granström
May 8, 2020·Radiation Oncology·Luiz Henrique Ferreira JúniorFlaviana Soares Rocha
Jan 16, 2014·Journal of Applied Biomaterials & Functional Materials·Arto P KoistinenReijo Lappalainen
Jun 29, 1999·The Journal of Prosthetic Dentistry·M T Marunick, E D Roumanas