PMID: 8945066Nov 1, 1996Paper

Effects of ischemia and reperfusion on QT dispersion during coronary angioplasty

Pacing and Clinical Electrophysiology : PACE
A MichelucciG F Gensini

Abstract

The effects of ischemia and reperfusion on QT interval dispersion (QTD: QTmax-QTmin in the 12-lead ECG) were analyzed in 15 patients (12 males, 57 +/- 13 years) undergoing coronary angioplasty (PTCA). All patients had single-vessel coronary artery disease (only one > or = 85% stenosis in a major coronary artery) and normal left ventricular function. All were in sinus rhythm with normal atrioventricular and intraventricular conduction on the surface ECG. No patient was on therapy that could affect the QT interval. The ECG was recorded (all 12 leads simultaneously) at 50 mm/s speed before the first balloon inflation, at the end of the first inflation during PTCA, and at 30" and 60" during reperfusion following the first inflation. In order to avoid ischemic preconditioning, only recordings of the first inflation were used. In each tracing QTmax and QTmin were evaluated. All values were rate corrected using a simple linear equation (QT linear corrected = QT + 0.154 [1-RR]). QTD increased significantly during both ischemia and reperfusion. QTmax was not changed by ischemia and was increased by reperfusion. QTmin was reduced by ischemia and increased by reperfusion. These results indicate that both ischemia and reperfusion alter ven...Continue Reading

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Citations

Apr 16, 1998·Journal of Electrocardiology·G TomassoniA Natale
Sep 5, 2002·International Journal of Cardiology·Milos KesekAnders Englund
Nov 25, 2000·Journal of the American College of Cardiology·M Malik, V N Batchvarov
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Aug 26, 1999·Pacing and Clinical Electrophysiology : PACE·M NakagawaM Ito
Nov 15, 2002·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Dalia GiedrimieneJeffrey Kluger
Jul 25, 2003·Pacing and Clinical Electrophysiology : PACE·Peter Van LeeuwenDietrich Grönemeyer

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