Effects of lead on the somatic growth of children

Archives of Environmental Health
A KafourouA Hatzakis

Abstract

Studies on the effects of lead on the somatic growth of children are limited and contradictory. The authors investigated the adverse effects of blood lead concentration on the somatic growth of primary-school-age children. In this study, there was a total of 522 children, aged 6-9 y, who resided in three areas of Greece (i.e., Loutraki, Lavrion, and Elefsina). The medical evaluation included medical history; physical examination; and measurements of height, head circumference, and chest circumference. The authors also evaluated dietary information, socioeconomic status, and height of parents. The authors conducted laboratory tests for hematological parameters and blood lead levels. The mean blood lead level was 12.3 microg/dl (standard deviation = 8.9 microg/dl), and levels ranged from 1.3 microg/dl to 51.2 microg/dl. There were negative monotonic relationships between growth parameters and blood lead levels, even after the authors allowed for confounding effects. An increase in blood lead level of 10 microg/dl was associated with a decrease of (a) 0.33 cm in head circumference (95% confidence interval = 0.12, 0.55; p = .002); (b) 0.86 cm in height (95% confidence interval = 0.14, 1.16; p = .020); and (c) 0.40 cm in chest circu...Continue Reading

References

Apr 1, 1979·Environmental Research·N E Johnson, K Tenuta
Jan 1, 1978·Pediatric Research·E E ZieglerS J Fomon
Sep 1, 1991·The American Journal of Clinical Nutrition·A R Frisancho, A S Ryan
Jul 1, 1991·Neurotoxicology and Teratology·T Greene, C B Ernhart
Jan 1, 1990·Cell Motility and the Cytoskeleton·A T HastieF P Colizzo
Feb 2, 1990·JAMA : the Journal of the American Medical Association·H L Needleman, C A Gatsonis
Jan 1, 1988·Journal of Child Psychology and Psychiatry, and Allied Disciplines·P A SilvaJ M Faed
Mar 1, 1986·Journal of Epidemiology and Community Health·A J McMichaelP D Clark
Sep 1, 1986·Archives of Environmental Health·C B ErnhartR J Sokol
Jan 1, 1986·American Journal of Physical Anthropology·M C LauwersJ Verheyden
Jan 1, 1984·American Journal of Industrial Medicine·M D RobertsonJ M Davis
Feb 1, 1984·The Journal of Clinical Endocrinology and Metabolism·P SaengerJ F Rosen
Nov 1, 1982·Archives of Environmental Health·R D RohnJ R Hill
Apr 1, 1982·Scottish Medical Journal·M R MooreA Low
Oct 1, 1982·Toxicology and Applied Pharmacology·J G PoundsR L Kodell
Jan 1, 1980·Archives of Environmental Health·S D WalterI H von Lindern
May 15, 1980·The New England Journal of Medicine·J F RosenK R Mahaffey
Jan 15, 1993·American Journal of Epidemiology·P KristensenA Andersen
Apr 1, 1991·Journal of Cross-cultural Gerontology·J Damron-Rodriguez

❮ Previous
Next ❯

Citations

Jun 5, 2010·Environmental Geochemistry and Health·Alecos DemetriadesIain Thornton
Jun 28, 2007·Indian Journal of Pediatrics·Manoochehr MahramFarnaz Sarkhosh
Mar 19, 2003·Archives of Environmental Health·Mauricio Hernandez-AvilaHoward Hu
May 13, 2008·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Donald T WigleDaniel Krewski
Jul 1, 2011·Environmental Health Perspectives·Myriam AfeicheMartha M Téllez-Rojo
Jul 17, 2008·Environmental Health Perspectives·Russ HauserPaige L Williams
May 2, 2013·Environmental Health Perspectives·Abby F FleischRuss Hauser
Apr 6, 2006·American Journal of Industrial Medicine·Pau-Chung ChenJung-Der Wang
Nov 11, 2008·American Journal of Human Biology : the Official Journal of the Human Biology Council·Lawrence M SchellElaine E Schulte
Aug 23, 2011·American Journal of Human Biology : the Official Journal of the Human Biology Council·Emanuele Sanna, Elisabetta Vallascas
Aug 5, 2000·International Journal of Occupational and Environmental Health·J LaDou
Apr 11, 2015·Environmental Health Perspectives·Eric E BeierRobert A Mooney
Nov 9, 2007·Environmental Research·Matthew R LambPam Factor-Litvak
Oct 30, 2015·Clinical Orthopaedics and Related Research·Caleb BehrendEdward Puzas
Jun 14, 2016·The Science of the Total Environment·Aikaterini SakellariMichael Scoullos
Jan 1, 2006·Clinical Pediatric Endocrinology : Case Reports and Clinical Investigations : Official Journal of the Japanese Society for Pediatric Endocrinology·Masayuki Kaji, Yoshikazu Nishi
Dec 26, 2018·BioMed Research International·Doan Ngoc HaiPham Minh Khue
May 23, 2019·International Journal of Toxicology·Mohamed A M KhalafHasan El-Fakahany

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.