Effects of Leisure-Time and Transport-Related Physical Activities on the Risk of Incident and Recurrent Myocardial Infarction and Interaction With Traffic-Related Air Pollution: A Cohort Study

Journal of the American Heart Association
Nadine J KubeschZorana Jovanovic Andersen

Abstract

Physical activity enhances the uptake of air pollutants, possibly reducing its beneficial effects. We examined the effects of leisure-time and transport-related physical activities on the risk of myocardial infarction (MI), and whether potential benefits on MI are reduced by exposure to traffic-related air pollution. A group of 57 053 participants (50-65 years of age) from the Danish Diet, Cancer, and Health cohort reported physical activity at baseline (1993-1997) and were linked to registry data on hospital contacts and out-of-hospital deaths caused by MI, until December 2015. Nitrogen dioxide levels were estimated at participants' baseline residences. We used Cox regressions to associate participation in sports, cycling, walking, and gardening with incident and recurrent MI, and tested for interaction by nitrogen dioxide. Of 50 635 participants without MI at baseline, 2936 developed incident MI, and of 1233 participants with MI before baseline, 324 had recurring MI during follow-up. Mean nitrogen dioxide concentration was 18.7 μg/m3 at baseline (1993-1997). We found inverse statistically significant associations between participation in sports (hazard ratio; 95% confidence interval: 0.85; 0.79-0.92), cycling (0.91; 0.84-0.98...Continue Reading

Associated Clinical Trials

Jul 29, 2019·Professor Jason Gill

References

Apr 15, 2003·Inhalation Toxicology·Christopher C DaigleMark W Frampton
Jun 11, 2003·American Journal of Epidemiology·Jens P HellermannVéronique L Roger
May 25, 2004·American Journal of Epidemiology·Maan JokhadarVéronique L Roger
Sep 23, 2006·Scandinavian Journal of Public Health·Sofia CarlssonAnders Ahlbom
Dec 5, 2006·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Patrik WennbergJan-Håkan Jansson
May 4, 2007·Preventive Medicine·Mark Hamer, Yoichi Chida
Jun 3, 2008·The International Journal of Behavioral Nutrition and Physical Activity·Anne E CustAdrian Bauman
Jun 6, 2008·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Marc NoconStefan N Willich
Apr 27, 2010·American Journal of Lifestyle Medicine·Mercedes R Carnethon
Mar 31, 2011·Medicine and Science in Sports and Exercise·Andrea K ChomistekEric B Rimm
Aug 4, 2011·Scandinavian Journal of Public Health·Carsten Bøcker Pedersen
Nov 18, 2011·European Journal of Epidemiology·UNKNOWN InterAct ConsortiumNick Wareham
Feb 18, 2012·JAMA : the Journal of the American Medical Association·Hazrije MustaficXavier Jouven
Aug 9, 2012·Future Cardiology·Mark R MillerJeremy P Langrish
Dec 12, 2012·The Canadian Journal of Cardiology·Alex WatkinsKumaraswamy Nanthakumar
Jan 8, 2014·Current Cardiovascular Risk Reports·Douglas DardenElizabeth A Jackson
Dec 11, 2014·European Heart Journal·David E NewbyUNKNOWN ESC Heart Failure Association
Apr 4, 2015·European Heart Journal·Sanjay SharmaLluis Mont
Apr 18, 2015·Current Problems in Cardiology·Barry A FranklinC Arden Pope
Apr 23, 2015·Preventive Medicine·Natalie MuellerMark Nieuwenhuijsen
Sep 18, 2015·Journal of Cardiopulmonary Rehabilitation and Prevention·Paolo GiorginiRobert D Brook
Nov 26, 2015·Clinical Epidemiology·Morten SchmidtHenrik Toft Sørensen
Jul 30, 2016·Environmental Health Perspectives·Maria MonradMette Sørensen
Aug 16, 2016·European Heart Journal·Nick TownsendMelanie Nichols
Sep 23, 2016·American Journal of Respiratory and Critical Care Medicine·Jack E FisherZorana J Andersen
Nov 17, 2016·World Journal of Cardiology·Alberto J AlvesFernando Ribeiro
Jul 1, 2017·European Journal of Preventive Cardiology·Kari PeersenJan E Otterstad

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Citations

Sep 11, 2019·International Journal of Epidemiology·Shengzhi SunLinwei Tian
Nov 7, 2019·Database : the Journal of Biological Databases and Curation·Chaoying ZhanBairong Shen
Nov 6, 2020·Circulation·Sanjay RajagopalanUNKNOWN American Heart Association Council on Lifestyle and Cardiometabolic Health; Council on Arteriosclerosis, Thrombosis and Vasc
Dec 23, 2020·Environment International·Marko TainioThiago Herick de Sá
Feb 12, 2021·Environmental Science and Pollution Research International·Fei Wang, Xinyu Wang
Apr 4, 2021·International Journal of Environmental Research and Public Health·Wasif RazaJohan Nilsson Sommar
Jun 21, 2021·International Journal of Hygiene and Environmental Health·Yiqian ZengXiang Qian Lao
Jul 3, 2021·International Journal of Environmental Research and Public Health·Regina GrazulevicieneInga Bendokiene
Oct 12, 2021·International Journal of Epidemiology·Yacong BoXiang Qian Lao
Dec 10, 2021·Neurology·Melissa A FurlongDavid A Raichlen

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Methods Mentioned

BETA
hormone replacement therapy

Software Mentioned

Stata
AirGIS

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