Effects of level and source of dietary selenium on maternal and fetal body weight, visceral organ mass, cellularity estimates, and jejunal vascularity in pregnant ewe lambs

Journal of Animal Science
T L NevilleJ S Caton

Abstract

Pregnant Targhee ewe lambs (n = 32; BW = 45.6 +/- 2.2 kg) were allotted randomly to 1 of 4 treatments in a completely randomized design to examine the effects of level and source of dietary Se on maternal and fetal visceral organ mass, cellularity estimates, and maternal jejunal crypt cell proliferation and vascularity. Diets contained (DM basis) either no added Se (control) or supranutritional Se from high-Se wheat at 3.0 ppm Se (SW) or from sodium selenate at 3 (S3) or 15 (S15) ppm Se. Diets were similar in CP (15.5%) and ME (2.68 Mcal/kg of DM) and were fed to meet or exceed requirements. Treatments were initiated at 50 +/- 5 d of gestation. The control, SW, S3, and S15 treatment diets provided 2.5, 75, 75, and 375 microg of Se/kg of BW, respectively. On d 134 +/- 10 of gestation, ewes were necropsied, and tissues were harvested. Contrasts, including control vs. Se treatments (SW, S3, and S15), SW vs. S3, and S3 vs. S15, were used to evaluate differences among Se levels and sources. There were no differences in ewe initial and final BW. Full viscera and liver mass (g/kg of empty BW and g/kg of maternal BW) and maternal liver protein concentration (mg/g) and content (g) were greater (P < 0.04) in Se-treated compared with cont...Continue Reading

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Citations

Jan 9, 2009·Reproduction : the Official Journal of the Society for the Study of Fertility·Anna T Grazul-BilskaKimberly A Vonnahme
May 25, 2011·Journal of Dairy Science·K A VonnahmeJ S Caton
May 16, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Yan MaXu Ma
Oct 4, 2018·Scientific Reports·A L SkibielJ Laporta
Jul 7, 2012·Journal of Animal Science·W C StewartJ A Hall
May 2, 2019·Reproduction, Fertility, and Development·Lingwei SunFeng Wang

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