Abstract
Pneumoperitoneum and the head-up position reportedly stimulate the sympathetic nervous system, potentially increasing the risk of cardiac arrhythmia. We evaluated the effects of a long duration of pneumoperitoneum in the head-up position on the heart rate-corrected QT (QTc) interval during robotic gastrectomy. This prospective observational study involved 28 patients undergoing robotic gastrectomy. The QTc interval was recorded at the following time points: before anaesthetic induction (baseline); 10 minutes after tracheal intubation; 1, 5, 30, 60, and 90 minutes after pneumoperitoneum induction in the head-up position; after pneumoperitoneum desufflation in the supine position; and at the end of surgery. The primary outcome was the QTc interval, which was measured 90 minutes after pneumoperitoneum combined with the head-up position. Compared with baseline, the QTc interval was significantly prolonged at 1 and 60 minutes after pneumoperitoneum, peaked at 90 minutes, and was sustained and notably prolonged until the end of surgery. However, no considerable haemodynamic changes developed. A long period of carbon dioxide pneumoperitoneum application in a head-up position significantly prolonged the QTc interval during robotic gast...Continue Reading
References
Feb 12, 1972·British Medical Journal·D B Scott, D G Julian
May 3, 2000·Surgical Endoscopy·N SatoK Inoue
Aug 13, 2002·Endoscopy·N UemuraY Nakaya
Oct 11, 2002·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Hirotoshi EgawaToshimitsu Kitajima
Nov 3, 2005·Acta Cardiologica·Emin SilayCihat Yagmur
Dec 24, 2005·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Yunlong XiaShiwen Yuan
Jan 18, 2006·Journal of the American College of Cardiology·Sabine M J M StrausJacqueline C M Witteman
Jun 15, 2006·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·H EgawaJ Minami
Mar 6, 2009·Surgical Endoscopy·Yahya EkiciMehmet Haberal
Dec 17, 2009·British Journal of Anaesthesia·S H KimY I Kim
Jul 22, 2010·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Michael FindlerSami Viskin
Jun 14, 2012·Anesthesiology·Peter NageleJoshua Johnston
Jul 31, 2013·Obesity Surgery·Ramon VilallongaManel Armengol
Dec 7, 2013·British Journal of Anaesthesia·C StaikouE Stavroulakis
Jan 1, 2014·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Orhan AlimogluTunc Eren
Feb 18, 2014·Yonsei Medical Journal·Youngsoon KimDong Woo Han
Oct 31, 2015·Annals of Surgical Innovation and Research·Pablo A AcquafrescaEdgardo Serra
Oct 6, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Gary Tse, Bryan P Yan
Jan 20, 2017·World Journal of Gastrointestinal Endoscopy·Stefano CarusoAndrea Coratti
Feb 1, 2017·Translational Gastroenterology and Hepatology·Seung Hyun LimHyoung-Il Kim
Apr 19, 2017·Journal of Forensic Sciences·John A GibbonsMark E Peele
Apr 27, 2017·Journal of Pain Research·Mohamad Farouk MohamadAlaa Ali M Elzohry