Effects of long-term reserpine treatment on brain tyrosine hydroxylase and behavioral activity

D S SegalA J Mandell


Treatment of rats with reserpine (for 8 or 9 days) produced a temporally related increase in behavioral activity and in tyrosine hydroxylase activity in the midbrain. Weight loss resulting from such treatment was not sufficient, by itself, to account for either the behavioral or enzymatic changes. The results support the role of catecholamines in behavioral arousal.


May 1, 1975·European Journal of Pharmacology·A E Halaris, D X Freedman
Jan 1, 1974·Journal of Psychiatric Research·A J Mandell
Sep 1, 1972·Neuropharmacology·A D Korczyn
Jan 1, 1976·Advances in Enzyme Regulation·R W Fuller, M Steinberg
Nov 1, 1979·Pharmacology, Biochemistry, and Behavior·T Palfai, T J Walsh
Feb 1, 1987·Pharmacology, Biochemistry, and Behavior·K L BruggeM H Aprison
Jan 1, 1973·Progress in Neurobiology·P L McGeer, E G McGeer
Feb 1, 1972·Behavioral Biology·D S SegalA J Mandell
Jul 21, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Victoria B RisbroughMark A Geyer
Sep 1, 1975·The Journal of Pharmacy and Pharmacology·D A Peters, I M Mazurkiewicz-Kwilecki
Dec 1, 1981·Journal of Neurochemistry·A J Mandell, P V Russo
Oct 1, 1988·Journal of Neurochemistry·G EisenhoferI J Kopin
Sep 1, 1984·Journal of Autonomic Pharmacology·L G Howes
Sep 1, 1976·Biulleten' eksperimental'noĭ biologii i meditsiny·V V Zakusov, M F Mineeva-Vialykh
Aug 1, 1975·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·G G Yarbrough, J W Phillis

Related Concepts

Behavior, Animal
Food Deprivation (Experimental)
Mixed Function Oxygenases
Rats, Laboratory

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