Effects of long-term temperature acclimation on thyroid hormone deiodinase function, plasma thyroid hormone levels, growth, and reproductive status of male Atlantic cod, Gadus morhua

General and Comparative Endocrinology
D G CyrJ G Eales

Abstract

The recent collapse of the Northwestern Atlantic cod fisheries has coincided with a cooling of water temperatures. During this time the condition factor of cod has been poor. The objective of the present study was to determine the effects of long-term temperature acclimation on growth reproduction and thyroid function in laboratory held Atlantic cod (Gadus morhua). One of the key parameters used to assess thyroid function is the peripheral metabolism of L-thyroxine (T4) by microsomal deiodinase enzymes. Deiodinase function has not been described for gadid fish. T4 outer-ring deiodinating activity (apparent K(m) 1-2 nM) was confined primarily to liver. Its properties resembled those for hepatic T4ORD activity of other teleosts and the mammalian type II deiodinase. The T4ORD activity of cod liver exceeded that of salmonids and could explain the high plasma T3 levels (10-18 ng/ml), which were 2-5 times greater than T4 levels. T4 and T3 inner-ring deiodination was confined mainly to brain. In order to determine the effects of long-term temperature acclimation on cod, somatic growth, reproduction, and thyroidal status were assessed monthly in 400-900-g satiation-fed male Atlantic cod captured in June from the St. Lawrence Estuary an...Continue Reading

Citations

Apr 8, 2009·General and Comparative Endocrinology·Benjamin de MontgolfierDaniel G Cyr
Apr 6, 2016·General and Comparative Endocrinology·José Ávila-MendozaCarlos Arámburo
Sep 21, 2007·Biology of Reproduction·Fernanda F L AlmeidaRüdiger W Schulz
Nov 14, 2000·The Journal of Experimental Zoology·J M McLeeseJ G Eales
Nov 27, 2020·Frontiers in Endocrinology·Cole K Deal, Helene Volkoff
Feb 6, 2018·Environmental Science & Technology·Lucas Buruaem MoreiraDaniel Schlenk

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