Effects of Losartan vs. Enalapril on the Markers of Metabolic Syndrome.

Oman Medical Journal
Zeina A Al-Thanoon, Isam H Mahmood

Abstract

To compare the effects of losartan and enalapril on the markers of metabolic syndrome. One hundred and twenty six newly diagnosed hypertensive patients having other markers of metabolic syndrome participated in this study. The study was performed in the department of pharmacology, college of medicine at Ibn-Sina Teaching Hospital in Mosul city, Iraq, during the period between December 2007 and June 2009. The patients were divided into 2 main groups: 1) Losartan group: consisted of 60 patients, and 2) enalapril group: Consisted of 66 patients. Waist circumference, weight, Body mass index, blood pressure, serum glucose concentration, triglyceride and HDL-cholestrol were measured before and after administration of therapy. The effects of therapy were assessed by statistically comparing the results before and after the drug administration. Comparison of waist circumference, blood pressure, FSG, triglycerides of the patients before drug administration (baseline data), with those of the controls showed a significant elevation, while HDL-cholesterol showed a significant reduction. A significant reduction of waist circumference, BP, FSG and a significant elevation of HDL-cholesterol were also noted after therapy with both losartan and ...Continue Reading

References

Feb 12, 2004·Kidney International·Aud HøieggenUNKNOWN LIFE Study Group
Dec 27, 2005·Current Pharmaceutical Design·S S DaskalopoulouM Elisaf
Sep 19, 2006·Metabolism: Clinical and Experimental·Sofia G TsouliMoses S Elisaf
Sep 26, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Vasilios G AthyrosMoses Elisaf
Mar 11, 2011·Current Vascular Pharmacology·Niki KatsikiDimitri P Mikhailidis
Nov 15, 2011·Current Pharmaceutical Design·Eirini LioudakiDimitri P Mikhailidis

❮ Previous
Next ❯

Citations

Apr 13, 2012·Oman Medical Journal·Michael S KostapanoDimitri P Mikhailidis
Jul 26, 2012·Experimental Diabetes Research·Rebecca Hutcheson, Petra Rocic
Mar 19, 2015·Peptides·Bilge AygenIbrahim Hanifi Ozercan

❮ Previous
Next ❯

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.