Effects of low frequency electromagnetic fields on expression of lymphocyte subsets and production of cytokines of men and women employed in a museum

The Science of the Total Environment
P BoscoloM Di Gioacchino

Abstract

The objective of this study was to analyse the immune response to electromagnetic fields (ELMFs) in seven men and eight women employed in a museum. The workers were exposed in a room to an ELMFs (range 0.2-3.6 microT and 40-120 V/m) induced by 50 Hz electricity for 20 h a week. Control groups consisted of 47 women and 39 men with a similar percentage of atopic subjects, age (range 30-51 years) and smoking habits of the workers included in the study. Levels of blood lead (Pb) and urinary trans-trans muconic acid, a metabolite of benzene (markers of exposure to traffic and smoking) of the control and exposed groups were similar. Lymphocyte subsets were determined in men and women using conjugated antibodies. Serum interleukin (IL) 4 and interferon gamma and their 'in vitro' production by peripheral mononuclear blood cells (PMBCs) stimulated by phytohemoglutinin (PHA), as well as blastogenesis of PMBCs induced by PHA, were determined in women only. ELMF-exposed women showed a significant reduction in the percentage of B and NK CD3(-)-CD25+ lymphocytes and a slight reduction of CD16(+)-56+ NK lymphocytes. They also showed significantly lower levels of interferon gamma in serum, or produced in the supernatants by PMBCs both spontane...Continue Reading

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Citations

Feb 11, 2005·Archives of Environmental Health·Laurence Bonhomme-FaivreHuguette Auclair
Feb 9, 2016·International Journal of Radiation Biology·Despoina MinaEfstratios D Valakos
Oct 11, 2012·Electromagnetic Biology and Medicine·Iraj SalehiAlireza Zamani
Dec 26, 2006·International Journal of Hygiene and Environmental Health·M SchwenkR Klein
Jan 7, 2015·Saudi Journal of Biological Sciences·C D'AngeloM Reale
Jul 30, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Haihui ZhangYuqing Duan
Feb 10, 2004·Journal of Occupational and Environmental Medicine·Travers Y IchinoseJohn S Reif
Dec 19, 2018·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Mahsa SobhanifardAlireza Zamani
Sep 4, 2004·International Journal of Immunopathology and Pharmacology·A BergamaschiG Somma
Nov 7, 2007·International Journal of Immunopathology and Pharmacology·P BoscoloS Di Luzio
Apr 11, 2018·Frontiers in Public Health·Maria Manuela RosadoClaudio Pioli

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