Effects of low serum triglyceride on stroke mortality: a prospective follow-up study

Atherosclerosis
Wi-Sun RyuByung-Woo Yoon

Abstract

Low serum triglyceride (TG) has been suggested as a predictor of mortality after cardiovascular disease. However, the relationship between the level of TGs and the outcome after stroke remains to be elucidated. We hypothesized that the influence of TG levels on post-stroke mortality varies according to stroke mechanism: cardioembolic (CE) vs. non-CE causes. We prospectively enrolled a consecutive series of patients with first-ever acute ischemic stroke for 5 years (n=1067), and followed them until the end of 2007 to obtain information on mortality and cause of death. We divided the level of TG into the quartiles, and classified the patients into CE (n=226) and non-CE stroke groups (n=841). The influence of TG level on mortality (all-cause death and vascular death) was examined by univariate and multivariate analyses using Cox regression. All-cause death and vascular death rates showed inverse relationships to the quartiles of TG levels in all patients (p<0.001, both) and also in non-CE stroke group (p<0.001, both), but not in CE stroke group (p=0.17 and p=0.37, respectively). In the Cox-regression analysis, compared with the highest quartile, the adjusted hazard ratio (HR) of the lowest quartile for all-cause death was 2.58 [95...Continue Reading

References

Apr 29, 1993·The New England Journal of Medicine·M H CriquiC E Davis
Jan 7, 1998·JAMA : the Journal of the American Medical Association·M W GillmanP A Wolf
Feb 28, 2001·American Journal of Epidemiology·H IsoY Komachi
Aug 28, 2002·Neurology·David W DesmondYaakov Stern
Mar 12, 2003·Proceedings of the National Academy of Sciences of the United States of America·Laura L ListenbergerJean E Schaffer
Apr 10, 2004·Stroke; a Journal of Cerebral Circulation·Tomasz DziedzicAndrzej Szczudlik
May 8, 2004·Stroke; a Journal of Cerebral Circulation·Tomasz DziedzicAndrzej Szczudlik
Dec 22, 2006·The New England Journal of Medicine·Sang Woo Oh
Dec 30, 2006·American Journal of Physiology. Gastrointestinal and Liver Physiology·Benny Hung-Junn Chang, Lawrence Chan
Apr 21, 2007·Stroke; a Journal of Cerebral Circulation·Angela M CarterPeter J Grant

❮ Previous
Next ❯

Citations

Apr 26, 2012·Rejuvenation Research·Damien BiottiJean-Raymond Teyssier
May 15, 2012·Journal of the Neurological Sciences·Kang-Ho ChoiKi-Hyun Cho
Dec 20, 2011·Atherosclerosis·Wi-Sun RyuByung-Woo Yoon
Jan 1, 2014·Australasian Journal on Ageing·Chia-Yu HsuYu-Ning Hu
Apr 17, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Slaven PikijaDunja Dukši
Jan 24, 2019·Lipids in Health and Disease·Tian-Li XiaDe-Jia Huang
May 1, 2020·The Journal of Clinical Endocrinology and Metabolism·Wendy A DavisTimothy M E Davis
Jan 1, 2013·Neuroscience Journal·Minal JainLatha Ganti Stead
Nov 20, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Q-W DengF-L Yan
Dec 15, 2019·Lipids in Health and Disease·Bumjo OhSohyun Chun
Sep 14, 2018·Frontiers in Neurology·Kai-Hung ChengUNKNOWN SRICHS Group
Aug 8, 2020·American Journal of Human Genetics·Allison MeisnerNilanjan Chatterjee
Nov 4, 2021·World Neurosurgery·Sauson SoldozyM Yashar S Kalani

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.