Effects of magnetic fields on the accumulation of thiobarbituric acid reactive substances induced by iron salt and H(2)O(2) in mouse brain homogenates or phosphotidylcholine

Pathophysiology : the Official Journal of the International Society for Pathophysiology
H KabutoR Liburdy

Abstract

In this study, we examined the effects of magnetic fields (MFs) on the generation of thiobarbituric acid reactive substances (TBARS) in the mouse brain homogenates or phosphotidylcholine (PC) solution, incubated with FeCl(3) and/or H(2)O(2). Active oxygen species were generated and lipid peroxidation was induced in mouse brain homogenates by incubation with iron ions, resulting in the accumulation of TBARS. Lipid peroxidation was induced in PC by incubation with iron ions and H(2)O(2). Exposure to sinusoidal MFs (60 Hz, 0.2-1.2 mT), symmetric sawtooth-waveform MFs (50 Hz, 25-600 mT/s), rectangular MFs (1/0.4-1/16 Hz, 3.3 mT) and static MFs (1, 5-300 mT) had no effect on the accumulation of TBARS in brain homogenates induced by FeCl(3). In contrast, when the homogenates were incubated with FeCl(3) in static MFs (2-4 mT), the accumulation of TBARS was decreased. However, this inhibitory effect disappeared when EDTA was added to the homogenate and incubated with H(2)O(2). The accumulation of TBARS in PC solution incubated with FeCl(3) and H(2)O(2) was also inhibited by the static MF. These results indicate that only static MFs had an inhibitory effect on iron-induced lipid peroxidation and the effectiveness of this magnetic field ...Continue Reading

References

Sep 24, 1992·Biochimica Et Biophysica Acta·J L PhillipsW R Adey
Mar 31, 1992·Annals of the New York Academy of Sciences·R P Liburdy
Aug 1, 1993·Journal of Cellular Physiology·E LindströmE Lundgren
Apr 1, 1993·American Industrial Hygiene Association Journal·D A Savitz
Dec 1, 1995·Journal of Occupational and Environmental Medicine·L I KheifetsZ W Zhang
Apr 4, 1998·Photochemistry and Photobiology·N MohtatJ Kim

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Citations

Sep 9, 2010·Cell Biochemistry and Biophysics·Mustafa EmreZeki Topcu
Jan 21, 2004·Journal of Photochemistry and Photobiology. B, Biology·Byung-Cheon LeeKwang-Sup Soh
Aug 6, 2000·Pathophysiology : the Official Journal of the International Society for Pathophysiology·R IshisakaK Utsumi
Sep 20, 2012·International Journal of Cell Biology·Claudia ConsalesBarbara Benassi
Jun 24, 2010·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Oluwatosin A AdaramoyeE Olatunde Farombi
Oct 19, 2006·Archives of Medical Research·Salem AmaraKhémais Ben Rhouma
Sep 13, 2013·BioMed Research International·Soumaya GhodbaneHafedh Abdelmelek
Dec 27, 2005·Brain Research Bulletin·A JelenkovićZ Prolić
Jul 23, 2013·International Journal of Molecular Sciences·Ewa KurzejaKatarzyna Pawłowska-Góral
Apr 23, 2019·Journal of Cellular Biochemistry·Neda MortazaviMoslem Abolhassani
Jul 29, 2020·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Marwa A A IbrahimNoha R M Elswaidy
Jan 24, 2020·The Journal of Chemical Physics·Nikita N LukzenRenad Z Sagdeev
May 20, 2017·Current Microbiology·Raouia HaniniAhmed Landoulsi

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