PMID: 1206631Nov 1, 1975Paper

Effects of maternal blood loss on embryonic and placental development in the rat

Journal of Reproduction and Fertility
N W Bruce, D A Cabral

Abstract

The effects of acute loss of maternal blood on embryonic and placental development was examined in 50 rats on Days 8 or 9 of gestation. Blood was withdrawn from conscious, cannulated rats over a 1-min period at 1-0 or 2-0 ml/100 g body weight. These degrees of blood loss were expected to produce a mild (about 50%) and severe (about 80%) reduction in uterine blood flow, respectively, for at least 15 min. There was no evidence that loss of blood affected either fetal survival and malformation rates or fetal weights and sex ratios. The anaemia resulting from haemorrhage lasted no longer than 6 days. Placental weights were 11% higher in rats losing 2-0 ml blood/100 g than in controls (P less than 0-05). It appears that the 8- or 9- day rat embryo is highly resistant to the partial reduction in uterine blood flow, maternal anaemia and other possible challenges induced by maternal loss of blood at levels sufficient to affect the mothers.

Citations

Jan 1, 1987·Experimental Gerontology·A Rahima, N W Bruce
Jan 25, 2012·Journal of Toxicologic Pathology·Satoshi FurukawaIzumi Ogawa
Dec 6, 2008·The Journal of Veterinary Medical Science·Satoshi FurukawaIzumi Ogawa
Mar 28, 2013·Toxicologic Pathology·J Mark ClineEberhard Buse
Apr 1, 1985·The Journal of Experimental Zoology·M J Soares, F Talamantes
Jun 4, 2016·International Journal of Experimental Pathology·K P SinghShrikant Gautam

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.