Effects of Matricaria Recutita (L.) in the Treatment of Oral Mucositis

TheScientificWorldJournal
Vânia Thais Silva GomesRenata Amadei Nicolau

Abstract

The objective of this study was to review the effects of the Matricaria recutita (L.) in the treatment of oral mucositis. The online search was performed in the period from June 2016 to April 2018 by means of databases LILACS (Latin American and Caribbean Center on Health Sciences Information), SciELO (Scientific Electronic Library Online), and MEDLINE (Medical Literature Analysis and Retrieval System Online). The consultation was restricted to the years 1991 to 2018 with the aim of elucidating the effects of Matricaria recutita in the treatment of oral mucositis. The final sample consisted of 21 studies, of which 10 were developed in animals and 11 in humans, published from 1991 to 2017, with a total sample of 644 patients. The total number of patients treated with Matricaria included in 11 studies was 364, while in the control groups the total number was 280. In experimental studies, animal models used were rats and the sample size ranged between 36 and 105 animals submitted to the induction of oral mucositis, where 4 studies used an intraperitoneal injection of 5-fluorouracil, while 7 induced lesion in the mucosa. From the data collected, it should be noted that both studies with humans and with animals showed significant ef...Continue Reading

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Citations

Nov 22, 2018·Frontiers in Pharmacology·Qing-Yu ZhangLing-Dong Kong
Apr 3, 2019·International Journal of Molecular Sciences·Agnieszka StempniewiczZygmunt Warzecha
Aug 28, 2020·Periodontology 2000·Isabelle Laleman, Wim Teughels
May 15, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Patrícia Leão Castillo EubankLuiz Evaristo Ricci Volpato
Oct 5, 2021·Basic & Clinical Pharmacology & Toxicology·Rodrigo Bitencourt Da RosaAlexandre De Barros Falcão Ferraz

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MEDLINE Literature Analysis and Retrieval System

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