PMID: 12859430Jul 16, 2003Paper

Effects of mild aerobic physical exercise on membrane fluidity of erythrocytes in essential hypertension

Clinical and Experimental Pharmacology & Physiology
K TsudaI Nishio

Abstract

1. The present study was undertaken to investigate the effects of aerobic physical exercise on membrane function in mild essential hypertension. 2. Hypertensive patients were divided into an exercise group (n = 8) and a non-exercise (control) group (n = 8). Physical exercise within the intensity of the anaerobic threshold level was performed twice a week for 6 months. Membrane fluidity of erythrocytes was examined by means of electron paramagnetic resonance (EPR) and spin-labelling methods before and after the trial period in both groups. 3. After physical exercise, blood pressure decreased significantly. 4. Compared with the non-exercise group, in the exercise group both the order parameter (S) and the peak height ratio (ho/h-1) in the EPR spectra of erythrocytes were significantly reduced (S, 0.717 +/- 0.004 vs 0.691 +/- 0.008, respectively (n = 8), P < 0.05; ho/h-1, 5.38 +/- 0.06 vs 4.89 +/- 0.06, respectively (n = 8), P < 0.05). These findings indicated that exercise increased membrane fluidity and improved the membrane microviscosity of erythrocytes. 5. There was no direct correlation between blood pressure reduction and the exercise-induced increase in membrane fluidity of erythrocytes. 6. In the non-exercise (control) gr...Continue Reading

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Citations

Dec 18, 2008·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Joanna BrzeszczynskaAnna Jegier
Jan 21, 2016·British Journal of Sports Medicine·Mats BörjessonBjörn Dahlöf
Oct 31, 2017·Clinical and Experimental Hypertension : CHE·Yutaka IgarashiSeiji Maeda
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Nov 2, 2018·Journal of Atherosclerosis and Thrombosis·Yutaka IgarashiSeiji Maeda
Jun 7, 2019·The Journal of Clinical Hypertension·Liujiao CaoKehu Yang
Dec 6, 2018·Journal of Clinical Medicine·Anne Kerstin ReimersCarl-Detlev Reimers

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