PMID: 653746Mar 1, 1978Paper

Effects of milk diet on gastrointestinal absorption of cadmium in adult mice

Toxicology
B Engström, G Nordberg

Abstract

Effect of milk diet on absorption of cadmium were investigated in a 6-week study. Forty adult male mice were divided into groups of 10 and treated with different foodstuffs (I: mouse pellets and deionized water; II: mouse pellets and water containing cadmium chloride: III: milk only: IV: milk containing cadmium chloride). The intake of cadmium and milk was regulated during the experiment to make sure that the animal groups received the same amounts of cadmium andmilk respectively. After 2 weeks the mice were exposed to a single oral dose via stomach tube of 109CdCl2, the fate of which was followed by whole body counting. A markedly higher whole body retention of 109CdCl2 was observed in animals given milk diet compared to other groups. Total cadmium concentrations in different organs measured by atomic absorption spectrophotometry were twice as high in milk-fed mice compared to mice fed on R35 mouse pellets.

References

May 1, 1977·Toxicology and Applied Pharmacology·D Kello, K Kostial
Oct 1, 1975·Food and Cosmetics Toxicology·R Stephens, H A Waldron
Sep 1, 1973·Environmental Research·D Kello, K Kostial

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Citations

Feb 1, 1987·Archives of Toxicology·B KargacinM Landeka
Mar 1, 1985·Biological Trace Element Research·G A JacklW E Kollmer
Jan 1, 1985·Journal of Toxicology and Environmental Health·L Leon, D R Johnson
Dec 1, 1979·Environmental Health Perspectives·R S Chhabra
Mar 1, 1984·Environmental Health Perspectives·K Kostial
Aug 15, 2000·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·T WlostowskiB Godlewska-Zylkiewicz
Jan 1, 1989·Critical Reviews in Toxicology·O Andersen

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