Effects of milnacipran on binge eating - a pilot study.

Neuropsychiatric Disease and Treatment
Shun'ichi NomaTakuji Hayashi

Abstract

Selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors are effective in the treatment of bulimia nervosa. There have been relatively few studies of the efficacy of specific serotonin and norepinephrine reuptake inhibitors in the treatment of eating disorders. Twenty-five outpatients with binge eating episodes, diagnosed as anorexia nervosa, binge-eating/purging type, bulimia nervosa/purging type, or bulimia nervosa/non-purging type, were treated with milnacipran and 20 patients completed the 8-week study. Symptom severity was evaluated using the Bulimic Investigatory Test, Edinburgh (BITE) self-rating scale before administration of milnacipran and after 1, 4, and 8 weeks treatment. The scores improved after 8 weeks, especially drive to, and regret for, binge eating. Milnacipran was more effective in patients without purging and in younger patients, while there was no difference in the efficacy of milnacipran among subtypes of eating disorders.

References

Jan 1, 1987·The British Journal of Psychiatry : the Journal of Mental Science·M Henderson, C P Freeman
Feb 1, 1996·Journal of Clinical Psychopharmacology·M M FichterJ Döhne
Sep 1, 1996·International Clinical Psychopharmacology·J Lopez-IborJ F Prost
Dec 8, 2000·International Clinical Psychopharmacology·N El-GiamalS Kasper
Oct 5, 2002·The Journal of Clinical Psychiatry·Shishuka MalhotraSusan L McElroy
Feb 8, 2003·Lancet·Christopher G Fairburn, Paul J Harrison
Mar 26, 2003·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Nadia El-GiamalSiegfried Kasper
Aug 6, 2003·The International Journal of Eating Disorders·William P CarterHarrison G Pope
Jan 1, 1959·The British Journal of Medical Psychology·M HAMILTON
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Sep 11, 2004·Journal of Psychopharmacology·Secondo FassinoAndrea Pierò
Dec 21, 2004·Advances in Therapy·W MilanoA Capasso
Jan 13, 2006·Journal of Psychopharmacology·Eric Hazen, Maurizio Fava

❮ Previous
Next ❯

Citations

Mar 29, 2011·The International Journal of Neuropsychopharmacology·Phillipa J Hay, Angélica M Claudino
Jul 12, 2011·The International Journal of Eating Disorders·Anna I GuerdjikovaJames I Hudson
Dec 14, 2018·CNS Drugs·Susan L McElroyFrancisco Romo-Nava

❮ Previous
Next ❯

Software Mentioned

BITE

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.