Effects of mitral chordae tendineae on the flow in the left heart ventricle

The European Physical Journal. E, Soft Matter
Valentina MeschiniRoberto Verzicco

Abstract

In this paper a computational model for the ventricular flow with a mitral valve and modeled chordae tendineae is presented. The results are compared with an analogous case in which the chordae are not included and their presence is replaced by kinematic boundary conditions. The problem is studied using direct numerical simulation of the Navier-Stokes equations, two-way coupled with a structural solver for the ventricle and mitral valve dynamics. An experimental validation of the model is performed by a comparison of the results with a companion dedicated experiment. It is found that the inclusion of the chordae tendineae makes the model self-consistent thus avoiding the use of ad hoc kinematic constraints to mimic their effect. In this way it is possible to simulate the correct system dynamics without user-defined parameters. More in detail, the results have shown that the mitral valve dynamics can be described also without chordae with the help of ad hoc kinematic constrains, whereas the changes produced in the intra-ventricular flow need the explicit consideration of the chordae in the model. On the other hand, the computational load increases owing to the presence of additional structures that, being thin filaments, are als...Continue Reading

References

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Jun 23, 2009·Journal of Biomechanics·Michael S SacksDavid E Schmidt
Apr 19, 2011·Journal of Biomechanics·M D de TullioR Verzicco

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Citations

Mar 9, 2019·The European Physical Journal. E, Soft Matter·Luca BiferaleFederico Toschi

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