PMID: 6411470Sep 15, 1983Paper

Effects of Mn2+, Ca2+ and chlorpromazine on photosystem II of Anacystis nidulans. An attempt to establish a functional relationship of amino acid oxidase to photosystem II

European Journal of Biochemistry
E K Pistorius

Abstract

Washing with EDTA changes the specificity of Anacystis nidulans particles having photosystem II activities for activation by cations. A specific requirement for Mn2+ and a somewhat lower specificity for Ca2+ can be demonstrated in the EDTA-washed particles. Both ions must be added to reconstitute the system evolving O2 in the light. EDTA-washed particles retain the L-amino acid oxidase with high specificity for the basic L-amino acids [Pistorius, E. K. and Voss, H. (1980) Biochem. Biophys. Acta, 611, 227-240] as well as the ability to reduce 2,6-dichloroindophenol with diphenylcarbazide as a donor in the light. The latter reaction which does not require added cations, can be inhibited by chlorpromazine, and this inhibition can be partially relieved by Ca2+ ions. Evidence is also presented that the L-amino-acid oxidase is inhibited by chlorpromazine, and this inhibition can be relieved by L-arginine in much the same way as the inhibition of the enzyme by Ca2+ ions can be relieved by L-arginine. The data are compatible with, but do not prove, an involvement of the L-amino-acid oxidase in the redox reactions of photosystem II of A. nidulans.

References

Dec 7, 1978·Biochimica Et Biophysica Acta·R G Piccioni, D C Mauzerall
Jul 1, 1968·European Journal of Biochemistry·F MüllerA Ehrenberg
Jan 27, 1983·Biochemical and Biophysical Research Communications·R W Mansfield, J Barber
Feb 14, 1980·Biochimica Et Biophysica Acta·E K Pistorius, H Voss
Feb 26, 1982·Biochemical and Biophysical Research Communications·R BarrF L Crane
Aug 1, 1982·European Journal of Biochemistry·E K Pistorius, H Voss
Jun 16, 1981·Biochemical and Biophysical Research Communications·C L DeRoo, C F Yocum

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