Effects of MR parameter changes on the quantification of diffusion anisotropy and apparent diffusion coefficient in diffusion tensor imaging: evaluation using a diffusional anisotropic phantom

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Sang Joon KimEun Ju Kim

Abstract

To validate the usefulness of a diffusional anisotropic capillary array phantom and to investigate the effects of diffusion tensor imaging (DTI) parameter changes on diffusion fractional anisotropy (FA) and apparent diffusion coefficient (ADC) using the phantom. Diffusion tensor imaging of a capillary array phantom was performed with imaging parameter changes, including voxel size, number of sensitivity encoding (SENSE) factor, echo time (TE), number of signal acquisitions, b-value, and number of diffusion gradient directions (NDGD), one-at-a-time in a stepwise-incremental fashion. We repeated the entire series of DTI scans thrice. The coefficients of variation (CoV) were evaluated for FA and ADC, and the correlation between each MR imaging parameter and the corresponding FA and ADC was evaluated using Spearman's correlation analysis. The capillary array phantom CoVs of FA and ADC were 7.1% and 2.4%, respectively. There were significant correlations between FA and SENSE factor, TE, b-value, and NDGD, as well as significant correlations between ADC and SENSE factor, TE, and b-value. A capillary array phantom enables repeated measurements of FA and ADC. Both FA and ADC can vary when certain parameters are changed during diffusion...Continue Reading

References

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Citations

Mar 2, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Duen-Pang KuoCheng-Yu Chen
May 15, 2018·Frontiers of Physics·Ileana O Jelescu, Matthew D Budde
Mar 17, 2019·Radiological Physics and Technology·Edna Marina de SouzaGabriela Castellano
Nov 12, 2016·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Mina Park, Won-Jin Moon
Sep 3, 2016·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Minjae Kim, Ho Sung Kim
Sep 3, 2016·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Eun Soo KimKwan Seop Lee
Aug 2, 2017·Asian Pacific Journal of Tropical Medicine·Xiang-Ying LiXiang-Jun Han
Dec 20, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Yeon Hyeon Choe

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