Effects of Nano-Composite Adsorbents on the Growth Performance, Serum Biochemistry, and Organ Weights of Broilers Fed with Aflatoxin-Contaminated Feed

Toxins
Mookiah SaminathanIdrus Zulkifli

Abstract

The exploration of feed mycotoxin adsorbents to mitigate the adverse effects of mycotoxins on animals has received increasing attention over the last decade. The present study was conducted to assess the efficacy of nano-composite magnetic graphene oxide with chitosan (MGO-CTS) adsorbents against feed contaminated with ~20 ng/g (ppb) aflatoxin (AF). A total of three hundred 1-day-old chicks were randomly distributed into six dietary treatment groups, as follows: basal diet (broilers fed a diet with neither AF nor MGO-CTS added, T1), basal diet + 0.25% MGO-CTS (T2), basal diet + 0.50% MGO-CTS (T3), AF diet + 0.25% MGO-CTS (T4), AF diet + 0.50% MGO-CTS (T5), and AF diet (T6). The two inclusion levels (0.25 and 0.50%) of MGO-CTS significantly (p < 0.05) improved the growth performances and feed conversion ratios of the AF-treated chicks at 1⁻35 days of age, and the impact was more pronounced for 0.5% MGO-CTS. The AF intake markedly increased the relative weights of the liver and kidney, resulting in significant alterations in the serum biochemical parameters, such as albumins, alkaline phosphatase, and SGPT/alanine (ALT), at 35 days of age. However, the chickens fed 0.5% MGO-CTS with AF diets had apparent recovery or restoration o...Continue Reading

References

Nov 1, 1975·Poultry Science·H T TungP B Hamilton
Oct 1, 1988·Poultry Science·W E HuffG E Rottinghaus
Mar 15, 2001·Toxicological Sciences : an Official Journal of the Society of Toxicology·S MathurW M Haschek
Jun 26, 2003·Critical Reviews in Food Science and Nutrition·H N Mishra, Chitrangada Das
Aug 25, 2010·ACS Nano·Daniela C MarcanoJames M Tour
Nov 15, 2014·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·S YibadatihanN A Mahyudin

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Citations

May 26, 2020·Toxicon : Official Journal of the International Society on Toxinology·Sabreen E FadlWalied S Abdo

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