Effects of nonsurgical periodontal treatment on glycated haemoglobin on type 2 diabetes patients (PARODIA 1 study): a randomized controlled trial in a sub-Saharan Africa population

BMC Oral Health
Nadia-Flore Tsobgny-TsagueEugene Sobngwi

Abstract

There is a burglar association between diabetes and periodontitis. Many studies has shown that periodontitis treatment can help improving glycemic control in diabetes patients but little evidence of non-surgical treatment benefit is available in sub Saharan african diabetes patients. We aimed to assess the effects of non-surgical periodontal treatment (NSPT) of chronic periodontitis on glycaemic control in poorly controlled type 2 diabetes patients (T2D) in a sub-Saharan Africa urban setting. A total of 34 poorly controlled T2D patients with chronic periodontitis aged 51.4 ± 8.8 years (mean ± SD), with known duration of diabetes of 55.5 ± 42.6 months, and HbA1c of 9.3 ± 1.3% were randomly assigned to two groups. The treatment group (Group 1, n = 17) received immediate ultrasonic scaling, scaling and root planning along with subgingival 10% povidone iodine irrigation, whereas the control group (Group 2, n = 17) was assigned to receive delayed periodontal treatment 3 months later. Pharmacological treatment was unchanged and all participants received the same standardized education session on diabetes management and dental hygiene. The primary outcome was the 3-month change in HbA1c from baseline. Plaque index (PI), gingival bleed...Continue Reading

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Citations

Jan 16, 2020·Journal of Applied Oral Science : Revista FOB·Mauricio BaezaJorge Gamonal
Jan 23, 2021·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Ya-Fei ChenLong-Jiang Li
Feb 22, 2021·International Dental Journal·Kostas KapellasLisa M Jamieson
May 1, 2021·International Journal of Environmental Research and Public Health·Sohail M NomanMuhammad Shafiq
Apr 30, 2021·Journal of Periodontal & Implant Science·Su Hwan KimYoung Sung Kim

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Clinical Trials Mentioned

NCT02745015

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SPSS Statistics

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