PMID: 7542557Jun 1, 1995Paper

Effects of nutrient solutions on concentration analysis of non-absorbable dilution markers--implications for studies of gastric emptying

Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society
A RühlM Wienbeck


Gastrointestinal luminal contents may interfere with concentration analysis of non-absorbable dyes. However, non-absorbable markers are broadly used for studies of gastric emptying rates of nutrient solutions. This prompted us to evaluate the properties of non-absorbable markers to mark such nutrient solutions. In vitro concentrations of polyethylene glycol, phenol red, dextran blue, two anthroquinone dyes and inulin were determined spectrophotometrically in the presence or absence of a formula diet, single compounds of the diet or an oligo-peptide diet, and the reproducibility and validity of the analyses were evaluated. The presence of the formula diet or the oligopeptide diet seriously impaired the analyses of marker concentrations, whereas single nutrient compounds did not uniformly interfere. The analysis of polyethylene glycol and phenol red concentrations was impaired by proteins, while the analysis of inulin concentration was impaired by carbohydrates. Dextran blue and the anthroquinones were completely eliminated by protein-precipitation procedures. In conclusion, phenol red and polyethylene glycol should only be used as marker substances for protein-free meals or nutrient solutions, while inulin should not be used wit...Continue Reading


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Apr 1, 1986·Journal of Pharmaceutical Sciences·M Fried, J H Meyer
Nov 1, 1986·Journal of Pharmaceutical Sciences·R L BronaughM Simon
May 1, 1986·Gastroenterology·S A Müller-Lissner
Mar 1, 1985·Journal of Pharmaceutical Sciences·J L DupasA F Hofmann
Apr 1, 1974·The American Journal of Digestive Diseases·I L MacGregor, J H Meyer
Mar 1, 1969·The American Journal of the Medical Sciences·G MooreE D Jacobson
Dec 10, 1954·The Journal of Physiology·J N HUNT, I MACDONALD
Jul 1, 1956·Journal of Applied Physiology·T H WILSON
Apr 1, 1951·The Journal of Physiology·J N HUNT, W R SPURRELL
Jun 1, 1951·Proceedings of the Society for Experimental Biology and Medicine·P L CALCAGNOM I RUBIN
Jan 1, 1945·The Biochemical Journal·E A Bradford, H Coke
Jan 1, 1949·Proceedings of the Society for Experimental Biology and Medicine·C D WEST, S RAPOPORT
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