Effects of obesity and smoking on mental stress-induced blood pressure and augmentation index responses in normotensive young males: the J-SHIPP study

Hypertension Research : Official Journal of the Japanese Society of Hypertension
Yasuharu TabaraMasamitsu Konishi

Abstract

Exaggerated blood pressure (BP) response to mental stress has been known to be a prognostic factor for cardiovascular disease. It has been argued that such unusual vascular reactivity to mental stress may arise from insulin resistance. To examine the vascular responses to mental stress, we evaluated the stress-related changes in BP and the augmentation index (AI), an index of arterial stiffness, in normotensive young males. Changes in late systolic BP (SBP2) representing central aortic pressure were also examined. Subjects were 86 males (21+/-2 years), 13 of whom were classified as obese (>or=25 kg/m(2)). AI was obtained from the radial arterial waveform as a ratio of the height of the late systolic peak to that of the first peak. Blood pressure and AI measurements were taken before, during and after a simple mental arithmetic test (MAT) lasting 3 min. Systolic BP (baseline 125+/-13, during MAT 133+/-13, post-MAT 124+/-11 mmHg; p<0.001) and heart rate (74+/-12, 81+/-13, 74+/-11 beats/min; p<0.001) were significantly increased during the MAT, whereas AI showed a slight reduction. In a separate analysis, the opposite response was observed between obese subjects showing increased AI (54+/-11, 56+/-13, 52+/-11%) and non-obese subje...Continue Reading

References

Oct 15, 1992·The American Journal of Cardiology·J K RockstrohF H Messerli
Aug 26, 1998·Stroke; a Journal of Cerebral Circulation·K A MatthewsS K Wolfson
May 16, 2000·The Journal of Physiology·I B WilkinsonD J Webb
Nov 7, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN Examination Committee of Criteria for 'Obesity Disease' in Japan, UNKNOWN Japan Society for the Study of Obesity
Jan 4, 2003·Hypertension·Azra Mahmud, John Feely
Apr 6, 2004·American Journal of Hypertension·Charalambos VlachopoulosChristodoulos Stefanadis
Apr 17, 2004·Stroke; a Journal of Cerebral Circulation·Shari R WaldsteinLeslie I Katzel
Feb 3, 2005·American Journal of Hypertension·Wilmer W Nichols
Feb 3, 2005·American Journal of Hypertension·Katsuhiko KoharaTetsuro Miki
Jul 12, 2005·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Louise M KellyMichael J Duffy
Oct 20, 2005·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yasuharu TabaraKatsuhiko Kohara
May 19, 2007·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kenji TakazawaAkira Yamashina

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Citations

Jun 14, 2012·Journal of Psychosomatic Research·Jeongok G LoganPamela J Rowsey
Jun 6, 2009·Journal of the American Geriatrics Society·Naomune YamamotoKuniaki Otsuka
Mar 27, 2010·American Journal of Hypertension·Namiko OchiTetsuro Miki
Apr 8, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·Hideaki ToyoshimaHiroshi Yatsuya
Jul 4, 2020·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Jeongok G LoganBrian H Annex
Oct 16, 2021·The Journal of Sports Medicine and Physical Fitness·Nobuhiko AkazawaSeiji Maeda
Aug 19, 2009·Current Opinion in Endocrinology, Diabetes, and Obesity

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