Effects of optimism on motivation in rats

Frontiers in Behavioral Neuroscience
Rafal RygulaPiotr Popik

Abstract

In humans, optimism is a cognitive construct related to motivation; optimists exert effort, whereas pessimists disengage from effort. In this study, using a recently developed ambiguous-cue interpretation (ACI) paradigm we took the unique opportunity to investigate whether "optimism" as a trait is correlated with motivation in rodents. In a series of ACI tests (cognitive bias screening, CBS), we identified rats displaying "pessimistic" and "optimistic" traits. Subsequently, we investigated the trait differences in the motivation of these rats to gain reward and to avoid punishment using a progressive ratio (PR) schedule of reinforcement paradigm. Although "optimistic" and "pessimistic" animals did not differ in their motivation to avoid punishment, the "optimistic" rats were significantly more motivated to gain reward than their "pessimistic" conspecifics. For the first time, we showed an association between cognitive judgment bias and motivation in an animal model. Because both investigated processes are closely related to mental health and wellbeing, our results may be valuable for preclinical modeling of many psychiatric disorders.

References

Dec 31, 1998·Experimental Brain Research·E M Bowman, V J Brown
Jan 6, 2000·Contemporary Educational Psychology·A Wigfield, J S Eccles
Nov 1, 1957·Psychological Review·J W ATKINSON
Jul 1, 1963·Journal of the Experimental Analysis of Behavior·W HODOS, G KALMAN
Jan 23, 2004·Nature·Emma J HardingMichael Mendl
Oct 4, 2006·Journal of Research in Personality·Suzanne C Segerstrom, Lise Solberg Nes
Mar 25, 2009·Journal of Personality and Social Psychology·Andrew L GeersG Daniel Lassiter
Jan 1, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Thomas EnkelBarbara Vollmayr
Feb 23, 2010·Clinical Psychology Review·Charles S CarverSuzanne C Segerstrom
May 14, 2010·Animal Cognition·Ben O BrilotMelissa Bateson
Oct 13, 2010·Current Biology : CB·Michael MendlRachel Casey
Jun 4, 2011·Current Biology : CB·Melissa BatesonGeraldine A Wright
Oct 11, 2011·Nature Neuroscience·Tali SharotRaymond J Dolan
Feb 15, 2012·Journal of Personality·Maria K Pavlova, Rainer K Silbereisen
Sep 7, 2012·PloS One·Emily J BethellStuart Semple
Jan 10, 2013·PloS One·Rafal RygulaPiotr Popik
May 11, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Rafal RygulaPiotr Popik
Sep 3, 2013·Behavioural Brain Research·Justyna PapciakRafal Rygula
Jan 1, 2007·Journal of Research in Personality·Suzanne C Segerstrom
Feb 8, 2014·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Rafal RygulaPiotr Popik
Mar 19, 2014·Trends in Cognitive Sciences·Charles S Carver, Michael F Scheier
Jul 1, 1997·Behavioural Processes·S A Ferguson, M G Paule
Aug 15, 2014·Psychopharmacology·Rafal RygulaPiotr Popik

❮ Previous
Next ❯

Citations

Dec 25, 2015·Behavioural Brain Research·Dominik RafaRafal Rygula
Feb 20, 2016·Expert Opinion on Drug Discovery·Kurt L Hoffman
Jul 5, 2016·Frontiers in Behavioral Neuroscience·Sanne RoelofsFranz Josef van der Staay
Jan 25, 2018·Scientific Reports·Benjamin LecorpsMarina A G von Keyserlingk
Feb 24, 2016·Cognitive, Affective & Behavioral Neuroscience·Rafal Rygula, Piotr Popik
Aug 4, 2019·Psychopharmacology·Karolina Noworyta-SokolowskaRafal Rygula
Nov 7, 2018·Scientific Reports·Benjamin LecorpsMarina A G von Keyserlingk
Oct 7, 2015·Journal of Applied Animal Welfare Science : JAAWS·Emily J Bethell
Feb 2, 2019·Frontiers in Neuroscience·Kenneth L Davis, Christian Montag
Apr 6, 2017·Frontiers in Behavioral Neuroscience·Joanna Golebiowska, Rafal Rygula
Jul 24, 2020·Animal Cognition·Aurélie VerjatChristophe Féron
Jan 9, 2021·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Karolina Noworyta, Rafal Rygula
Aug 30, 2021·Neuroscience and Biobehavioral Reviews·Benjamin LecorpsMarina A G von Keyserlingk

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Rafal RygulaPiotr Popik
Trends in Cognitive Sciences
Charles S Carver, Michael F Scheier
© 2021 Meta ULC. All rights reserved