Effects of oral glutamine supplementation on children with solid tumors receiving chemotherapy

Pediatric Hematology and Oncology
Arzu OkurCeyda Karadeniz

Abstract

In recent years, there have been reports that glutamine support improves immune functions in adult patients with malignancy, but there is a lack of data in children. Oral glutamine support of 4 g/m2/day was given to 21 children with various solid tumors, aged 1-17 years (9.86 +/- 5.38) for all 5 days of a chemotherapy course. The same parameters in another course of the same protocol without glutamine supplementation were considered as controls. There were significant improvements of some nutritional and immunological parameters in the glutamine-supplemented course. Also glutamine seemed to reduce antibiotic necessity. Oral glutamine supplementation could be considered in children with solid tumors receiving chemotherapy.

References

Aug 1, 1991·Journal of Pediatric Surgery·M GreenbergA Balcolm
Aug 1, 1990·Nutrition Reviews·J M Lacey, D W Wilmore
Apr 1, 1990·The Journal of Surgical Research·V S KlimbergE M Copeland
Jun 1, 1974·Journal of Applied Physiology·J BergströmE Vinnars
Jan 1, 1995·Annals of Surgical Oncology·D L BartlettM H Torosian
May 29, 1993·Lancet·R R van der HulstP B Soeters
Jul 1, 1997·JPEN. Journal of Parenteral and Enteral Nutrition·R J Smith
Jul 1, 1997·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C GirouardM Crump
May 25, 1999·JPEN. Journal of Parenteral and Enteral Nutrition·L KouznetsovaA P Houdijk
Sep 1, 1999·Clinical and Experimental Immunology·W K ChangM F Shaio
Sep 14, 1999·JPEN. Journal of Parenteral and Enteral Nutrition·B A van AckerP B Soeters
Jan 30, 2003·Pediatric Hematology and Oncology·Hubert MottlShafika Al Awadi
Dec 6, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S LaskarK A Dinshaw
Jul 16, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James S MiserHolcolmbe E Grier
Nov 13, 2004·The Journal of Nutritional Biochemistry·P NewsholmeM Pires de Melo

❮ Previous
Next ❯

Citations

Nov 6, 2010·Sarcoma·Vivek Subbiah, Pete Anderson
Dec 17, 2011·Journal of Nutrition and Metabolism·Elise Mok, Régis Hankard
Aug 25, 2012·Expert Opinion on Investigational Drugs·Teresa Stachowicz-Stencel, Anna Synakiewicz
Sep 25, 2018·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Elena J Ladas
Nov 26, 2009·European Journal of Nutrition·Katharina S KuhnPeter Stehle
Jul 3, 2020·Pediatric Blood & Cancer·Caroline DiorioStacey Marjerrison
Aug 25, 2015·The Cochrane Database of Systematic Reviews·Evelyn J WardRobert S Phillips
Oct 14, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Andrea L RadossiElena J Ladas
Feb 22, 2013·Journal of Pediatric Hematology/oncology·Zuhal K YildirimMustafa Buyukavci
Jun 2, 2021·Pediatric Blood & Cancer·Jong H ChungEllen B Fung

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.