Effects of oral nutritional supplements in normally nourished or mildly undernourished geriatric patients after surgery for hip fracture: a randomized clinical trial

JPEN. Journal of Parenteral and Enteral Nutrition
José I Botella-CarreteroClotilde Vázquez

Abstract

Oral nutritional supplements have been recommended after orthopedic surgery in geriatric patients to reduce postoperative complications. However, tolerability of supplements could be a limitation, and their universal use is not supported by the heterogeneity of previous studies, especially in patients without malnutrition. This study is a randomized, controlled, open, parallel, 3-arm clinical trial comparing supplementation with protein powder dissolved in liquids to aim at 36 g of protein per day, energy and protein supplements to aim at 37.6 g of protein and 500 kcal per day, or no intervention in normally nourished or mildly undernourished patients. Outcomes were serum albumin, prealbumin, retinol-binding globulin, and body mass index, among others. Postoperative complications were also recorded. Ninety patients aged 83.8 +/- 6.6 years were included. The mean ingested amount of supplements was 41.1% +/- 20.6% in the protein powder supplement group and 51.4% +/- 13.2% in the energy protein supplement group (t = 2.278, P = .027). Postoperative supplements had no effect on the nutrition status during in-hospital follow-up, as assessed by serum albumin (P = .251), prealbumin (P = .530), retinol-binding globulin (P = .552), or bo...Continue Reading

References

Oct 1, 1992·Journal of the American College of Nutrition·L TkatchJ P Bonjour
May 1, 1996·Clinical Orthopaedics and Related Research·G C Del SavioK A Ende
Jun 22, 1999·Journal of the American College of Nutrition·C J LaverniaL Baerga
Jul 15, 2000·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·R M LawsonI Cobden
Jan 30, 2003·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·R M LawsonI Cobden
May 16, 2003·The New England Journal of Medicine·Mariell Jessup, Susan Brozena
Jul 25, 2003·European Journal of Clinical Nutrition·A Avenell, H H G Handoll
Aug 7, 2004·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Jan TidermarkTommy Cederholm
Sep 28, 2004·The Journal of Bone and Joint Surgery. British Volume·J Aderinto, I J Brenkel
Apr 13, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Pawel SzulcPierre D Delmas
Apr 23, 2005·The Cochrane Database of Systematic Reviews·A Avenell, H H G Handoll
Apr 23, 2005·The Cochrane Database of Systematic Reviews·A C MilneA Avenell
Oct 8, 2005·The American Journal of Clinical Nutrition·Nadya KaganskyShmuel Levy
Jan 31, 2006·Archives of Physical Medicine and Rehabilitation·Devora LiebermanDavid Lieberman
May 16, 2006·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Matthias PirlichHerbert Lochs
Jun 14, 2006·Clinical Orthopaedics and Related Research·Magnus EnerothKarl-Göran Thorngren
Aug 1, 1990·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·J LarssonP Bjurulf
Sep 9, 2006·The American Journal of Clinical Nutrition·Robert R Wolfe
Sep 29, 2006·Orthopedics·Viktor E KrebsRobert Helfand
Oct 28, 2006·Acta Orthopaedica·Margareta HedströmTommy Cederholm
Jul 3, 2007·Archives of Physical Medicine and Rehabilitation·Avital HershkovitzShai Brill

❮ Previous
Next ❯

Citations

Nov 26, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D MarslandS L Kates
Jun 12, 2013·Canadian Journal of Physiology and Pharmacology·Jack BellChrys Ranjeev Pulle
Aug 6, 2010·Archives of Gerontology and Geriatrics·Bryan J PimlottSumit R Majumdar
Mar 5, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·José I Botella-CarreteroClotilde Vázquez
Oct 30, 2016·The Journal of Nutrition, Health & Aging·J van WissenA P J Houdijk
Jan 20, 2012·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Gary P HubbardRebecca J Stratton
Jan 7, 2014·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Jack J BellRanjeev Chrys Pulle
Sep 11, 2016·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Tatsuro InoueRei Ono
Dec 10, 2013·JPEN. Journal of Parenteral and Enteral Nutrition·Michael J CangelosiJoshua T Cohen
Jun 18, 2017·Journal of Evaluation in Clinical Practice·Ellen B Babb, James Rohrer
Jul 8, 2017·Journal of the American College of Nutrition·Taylor C Wallace, Cara L Frankenfeld
Dec 21, 2016·The Cochrane Database of Systematic Reviews·Christine BaldwinChristine Elizabeth Weekes
May 20, 2017·The Cochrane Database of Systematic Reviews·Joshua FeinbergJanus C Jakobsen
Sep 9, 2011·The Cochrane Database of Systematic Reviews·Christine Baldwin, Christine Elizabeth Weekes
Sep 25, 2018·Journal of Orthopaedic Trauma·Alexandra ErnstMara L Schenker
Jan 28, 2014·Journal of Orthopaedic Trauma·Benjamin S ZellnerCharles A Reitman
Dec 27, 2019·Journal of Clinical Nursing·Debbie Ten CateUNKNOWN Basic Care Revisited Group (BCR)
Nov 30, 2016·The Cochrane Database of Systematic Reviews·Alison AvenellPhyo K Myint
Sep 12, 2018·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Caroline E WyersPieter C Dagnelie
Nov 2, 2019·Geriatric Orthopaedic Surgery & Rehabilitation·James ArkleyWilliam Eardley
Jun 12, 2021·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Johannes Dominik BastianAndreas Ernst Stuck
Dec 22, 2021·The Cochrane Database of Systematic Reviews·Christine BaldwinChristine Elizabeth Weekes

❮ Previous
Next ❯

Software Mentioned

Ene
SPSS

Related Concepts

Related Feeds

Cell Aging (Keystone)

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.