Aug 1, 1976

Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics

British Journal of Clinical Pharmacology
R F WilleyS J Pocock


In a double-blind trial the effects on ventilatory function (FEV1), heart rate and blood pressure of oral pirbuterol and oral salbutamol in various single doses were studied in ten patients with chronic asthma. Pirbuterol (15 mg) and salbutamol (4 mg) produced equal peak levels of bronchodilatation. There was no significant difference in the mean rise in heart rates caused by the two drugs, and no other significant side-effects were noted.

  • References2
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  • References2
  • Citations9


Mentioned in this Paper

Pirbuterol sulfate
Diastolic Blood Pressure
Broncholytic Effect
Blood Pressure
Forced Expiratory Volume Function

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