PMID: 7015875May 1, 1981Paper

Effects of ovarian steroids and pregnancy on adrenergic nerves of uterus and oviduct

The American Journal of Physiology
J M Marshall

Abstract

This review concerns the influence of ovarian steroids and of pregnancy on norepinephrine (NE) metabolism in the adrenergic neurons of the female reproductive tract and speculates on the physiological consequences of this influence. Estrogen and progesterone affect not only the NE content of these nerves but also the turnover of NE, the activity of its synthetic enzyme, and releases of NE from nerve terminals. During pregnancy additional factors including stretch-induced hypertrophy come into play and cause degeneration of the nerves in the uterine corpus. This degeneration makes the muscle supersensitive to NE and may also induce morphological changes in the muscle cell membrane. As a result there may be a withdrawal of neural inhibitory influences on the corpus, allowing spontaneous myogenic contractions to intensify. Although the physiological significance of the steroid-transmitter interactions are still unclear, these nerves per se are of interest because they represent a model system for the study of neuroendocrine regulation in the peripheral nervous system.

References

Jan 1, 1977·Annual Review of Pharmacology and Toxicology·P Hedqvist
Oct 1, 1977·The Journal of Clinical Investigation·L T Williams, R J Lefkowitz
Oct 1, 1977·Physiological Reviews·T C Westfall
May 1, 1979·Canadian Journal of Physiology and Pharmacology·E Zelcer, E E Daniel
Jan 1, 1978·Acta Obstetricia Et Gynecologica Scandinavica·G ThorbertE Rosengren
Jan 21, 1977·European Journal of Pharmacology·D P WestfallW W Fleming
Jan 7, 1977·Journal of Theoretical Biology·N Sperelakis, J E Mann
Apr 1, 1976·The Journal of Physiology·M OhbaT Tomita
Mar 1, 1974·Biology of Reproduction·J BahrA V Nalbandov
Jan 1, 1970·Annual Review of Pharmacology·N Weiner
Apr 1, 1971·American Journal of Obstetrics and Gynecology·S GårdmarkN O Sjöberg
Aug 1, 1970·Biology of Reproduction·M W Rüsse, J M Marshall
Jan 1, 1973·Zeitschrift für Zellforschung und mikroskopische Anatomie·A Hervonen, L Kanerva
May 1, 1973·British Medical Bulletin·L L Iversen
Dec 1, 1974·British Journal of Pharmacology·M Hollingsworth
Jan 1, 1974·Gynecologic Investigation·R E Garfield, E E Daniel
Dec 1, 1969·Biology of Reproduction·A R Fuchs
Mar 1, 1980·Acta Physiologica Scandinavica·M ElmérG Thorbert
Mar 1, 1954·Journal of Applied Physiology·R CALDEYRO-BARCIA, H ALVAREZ

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Citations

Apr 1, 1989·Zentralblatt für Veterinärmedizin. Reihe A·G Thilander, H Rodriguez-Martinez
Oct 1, 1994·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M M BrauerG Burnstock
Mar 25, 2017·Biology of Reproduction·Alfredo Ramírez-RevecoIlona I Concha
Apr 1, 1994·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M M BrauerG Burnstock
Jul 17, 1998·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M M Brauer, G Burnstocks
Jul 14, 2006·Reproduction, Fertility, and Development·R Chávez-GenaroG Anesetti
Jun 1, 1984·Naunyn-Schmiedeberg's Archives of Pharmacology·J A KennedyR G Morris
Sep 9, 1999·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M M BrauerT Cowen
Dec 1, 1995·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M M BrauerG Burnstock
Feb 22, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Nimrod MarilHadassa Degani
Jun 13, 2013·Fertility and Sterility·Maria L Barcena de ArellanoSylvia Mechsner

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