PMID: 2506373Jul 1, 1989Paper

Effects of parenteral nutrition on whole body and extremity composition in children and adolescents with active inflammatory bowel disease

JPEN. Journal of Parenteral and Enteral Nutrition
C H LinE Lebenthal

Abstract

The effect of parenteral nutrition (PN), combined with corticosteroid therapy, on body composition was evaluated in 22 pediatric patients with active and complicated inflammatory bowel disease (IBD). The patients were divided into two groups according to the duration of PN. Group A consisted of 14 patients who received PN for an average of 43 days (short term) whereas eight patients received PN for an average of 104 days (long term); group B. Nutritional assessments were performed before and following the PN periods. In addition, a follow-up assessment was performed 50 days after the cessation of PN for group A. Serial evaluations included; weight, height, disease activity score, arm anthropometry, subscapular skinfold (SSSF) thickness, 24-hr urinary creatinine, and computed tomography (CT) scan of the thigh. Following PN with a glucose-fat mixture used as a nonprotein energy source, there were significant (p less than 0.05) increases in weight, SSSF, and muscle mass (MM) in both groups. Disease activity declined in both groups and height increased in group B and at the follow-up assessment for group A. Considering extremity composition, both groups exhibited increases in midarm muscle area, midarm fat area, thigh muscle area, ...Continue Reading

References

Mar 1, 1979·The American Journal of Clinical Nutrition·S B HeymsfieldD W Nixon
Aug 1, 1979·Digestive Diseases and Sciences·J D Lloyd-Still, O C Green
Jun 1, 1978·Scandinavian Journal of Clinical and Laboratory Investigation·T HäggmarkB Svane
Oct 1, 1987·American Journal of Diseases of Children·C H LinE Lebenthal
Aug 15, 1985·The New England Journal of Medicine·F ShannN Crinis
Feb 1, 1973·American Journal of Surgery·J E FischerJ A Ryan
Mar 1, 1983·The American Journal of Clinical Nutrition·S B HeymsfieldS Moffitt

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Citations

Apr 4, 2014·World Journal of Gastroenterology : WJG·Rebecca J Hill
Aug 6, 2008·Pediatric Research·Steven J SteinerScott C Denne
Mar 27, 2003·Inflammatory Bowel Diseases·Johanna C EscherRichard J Grand
Jun 1, 1991·Gut·M C de KaskiH J Hodgson

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