PMID: 8950007Nov 1, 1996Paper

Effects of parietal cortex lesions on spatial problem solving in the rat

Behavioural Brain Research
C Thinus-BlancN Foreman

Abstract

The Maier 3-table task was used to examine spatial representations in rats with lesions of the parietal cortex. Some animals had anteriorly placed lesions, some posteriorly placed in cortical areas, sometimes regarded as 'parietal' in earlier studies. After 5 days of familiarization, animals were given 18 days of testing on the standard Maier task. Both parietal groups were initially impaired, but reached the same level of performance as controls by the end of the test period. Learning occurred both within and between sessions for the anterior group, but only between sessions for the posterior group. There was no major functional differentiation apparent on this task between the two 'parietal' areas. Rate of exploration increased in both parietal groups across test sessions as task performance improved. It is argued that the change in exploratory activity across sessions in parietal groups may reflect the adoption of a compensatory strategy which improved performance, but that improvement could also have been due to neural changes, as structures, such as the frontal cortex or hippocampus, assume some functions normally mediated by the parietal area.

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Citations

Mar 18, 2000·Journal of Neuroscience Methods·D DraiI Golani
Dec 1, 1999·Neuroscience·M EijkenboomF J van der Staay
Oct 6, 1998·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·C Thinus-BlancB Poucet
Aug 23, 2003·Behavioral Neuroscience·Elvira De LeonibusAndrea Mele
Jul 4, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Virginie Da Silva CostaFrançois Dauphin
Jun 22, 2006·Learning & Behavior·Michael F Brown, Gary W Giumetti
Mar 13, 1999·Annual Review of Psychology·E A CapaldiS E Fahrback
Apr 3, 2009·Neurobiology of Learning and Memory·Francesca GelfoMaria Giuseppa Leggio
Aug 4, 2004·Experimental Gerontology·P LiuD K Bilkey
Aug 17, 2010·Behavioural Processes·Viviana Vargas-LópezAlejandro Múnera
Oct 4, 2006·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jean-Pierre Changeux
Dec 4, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Elodie MordeletSylvie Granon

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