Effects of polyamines and polyamine biosynthetic inhibitors on mitotic activity of Allium cepa root tips

Acta Biologica Hungarica
Meral UnalM A Tufekci

Abstract

The genotoxic and cytotoxic effects of exogenous polyamines (PAs), putrescine (Put), spermidine (Spd), spermine (Spm) and PA biosynthetic inhibitors, alpha-difluoromethylornithine (DFMO), cyclohexilamine (CHA), methylglioxal bis-(guanylhydrazone) (MGBG) were investigated in the root meristems of Allium cepa L. The reduction of mitotic index and the induction of chromosomal aberrations such as bridges, stickiness, c-mitotic anaphases, micronuclei, endoredupliction by PAs and PA biosynthetic inhibitors were observed and these were used as evidence of genotoxicity and cytotoxicity.

References

Sep 1, 1979·Experimental Cell Research·M H Goyns
Jan 1, 1992·International Review of Cytology·D M Hougaard
Aug 1, 1994·Cytometry·P PohjanpeltoS Knuutila
Apr 6, 2001·Cellular and Molecular Life Sciences : CMLS·T Thomas, T J Thomas
Feb 1, 1980·Plant Physiology·R Kaur-SawhneyA W Galston

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