Effects of poverty on interacting biological systems underlying child development

The Lancet Child & Adolescent Health
Sarah K G JensenCharles A Nelson

Abstract

The developmental sequelae of childhood poverty are well documented. However, it is not poverty per se, but a multitude of risk factors associated with poverty that have a deleterious effect on children's development. Key risks factors that are likely to contribute to the adverse developmental effects of poverty include, for instance, food insecurity, infectious disease, and psychological stress related to the child's rearing environment. In this Review, we highlight synergistic biological pathways through which co-occurring risks related to poverty interact to shape children's neurocognitive development. We focus on pathways related to neural growth, energy metabolism, inflammation, and neuroendocrine responses to stress as key biological axes through which poverty becomes biologically embedded and might have long-term effects on children's neurocognitive development. We also discuss how biomarkers targeting these axes can be used to advance research on the biological processes through which poverty affects children's cognitive outcomes. Although the discussion has global relevance, we focus on low-resource settings where rates of poverty are highest and access to treatment might be limited.

References

Feb 7, 2001·Annual Review of Psychology·G Margolin, E B Gordis
Dec 26, 2001·Annual Review of Psychology·Robert H Bradley, Robert F Corwyn
Apr 18, 2003·Journal of Consulting and Clinical Psychology·Katherine M KitzmannErin D Kenny
Jun 23, 2004·Neurobiology of Disease·Praveen BallabhMaiken Nedergaard
Jul 23, 2005·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Peter D PatrickRichard L Guerrant
Aug 15, 2006·Annual Review of Psychology·Megan Gunnar, Karina Quevedo
Dec 15, 2006·Nature·Gökhan S Hotamisligil
Apr 3, 2008·The Journal of Clinical Investigation·William A PetriRichard L Guerrant
Nov 21, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Rebecca C KnickmeyerJohn H Gilmore
Jan 6, 2009·Monographs of the Society for Research in Child Development·Marian J Bakermans-KranenburgFemmie Juffer
Jan 13, 2009·Trends in Cognitive Sciences·Daniel A Hackman, Martha J Farah
Apr 30, 2009·Nature Reviews. Neuroscience·Sonia J LupienChristine Heim
Oct 2, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Gregory Z Tau, Bradley S Peterson
Oct 14, 2009·Neuroscience and Biobehavioral Reviews·Robert-Paul JusterSonia J Lupien
Nov 13, 2009·Annals of the New York Academy of Sciences·Thaddeus W W Pace, Andrew H Miller
Mar 6, 2010·Annals of the New York Academy of Sciences·Bruce S McEwen, Peter J Gianaros
Jul 27, 2010·Current Opinion in Clinical Nutrition and Metabolic Care·Xin ZhouGeorge A Kuchel
Mar 3, 2011·International Journal of Epidemiology·Florencia Torche, Ghislaine Echevarría
Jul 16, 2011·Development and Psychopathology·Clancy BlairUNKNOWN Family Life Project Key Investigators
Nov 24, 2011·Cerebral Cortex·John H GilmoreDinggang Shen
Nov 24, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Dinesh MondalWilliam A Petri
Mar 21, 2012·The Proceedings of the Nutrition Society·Fátima Pérez de HerediaAscensión Marcos
Jun 26, 2012·Psychoneuroendocrinology·Natalie SlopenKarestan C Koenen
Oct 31, 2012·Brain, Behavior, and Immunity·Natalie SlopenKarestan C Koenen
Jun 12, 2013·Lancet·Robert E BlackUNKNOWN Maternal and Child Nutrition Study Group
Jul 3, 2013·Proceedings of the National Academy of Sciences of the United States of America·Helen J NevilleElif Isbell
Sep 17, 2013·Developmental Science·Przemyslaw TomalskiElena Kushnerenko
Dec 18, 2013·Child Development·Ann S Masten
Feb 28, 2014·Annals of the New York Academy of Sciences·Francis M NgureRebecca J Stoltzfus
Apr 2, 2014·Nutrition Reviews·Elizabeth L Prado, Kathryn G Dewey
Apr 24, 2014·The Journal of Physiology·Giada De PalmaElena F Verdu

❮ Previous
Next ❯

Citations

Feb 17, 2019·Developmental Science·Sarah Lloyd-FoxUNKNOWN BRIGHT project team
Oct 24, 2019·JAMA Psychiatry·Christian HakulinenPearl L H Mok
Mar 7, 2019·Scientific Reports·Sarah K G JensenCharles A Nelson
Feb 11, 2020·Developmental Science·Seth D Pollak, Barbara L Wolfe
Sep 13, 2019·American Journal of Human Biology : the Official Journal of the Human Biology Council·R Isabel CandoMarcela Guerendiain
Nov 24, 2019·Developmental Science·Sophie von StummRobert Plomin
Jul 14, 2020·International Journal of Radiation Biology·Lawrence A Kapustka
Mar 29, 2019·Annual Review of Sociology·Kathleen Mullan Harris, Kristen M Schorpp
Oct 18, 2019·American Journal of Public Health·Lia C H Fernald, Wendi Gosliner
Dec 11, 2019·Paediatric and Perinatal Epidemiology·Natalie A StrobelDaniel R McAullay
Aug 6, 2020·International Journal of Environmental Research and Public Health·Frances M NilsenNicolle S Tulve
Feb 13, 2020·The Canadian Journal of Nursing Research = Revue Canadienne De Recherche En Sciences Infirmières·Carla GinnKaren Benzies
Jan 12, 2021·Development and Psychopathology·Seth D Pollak, Barbara L Wolfe
Dec 8, 2020·Journal of Christian Nursing : a Quarterly Publication of Nurses Christian Fellowship·Breanna Lathrop
Dec 29, 2020·Developmental Psychobiology·Randi A BatesLaura Justice
Mar 1, 2019·Developmental Review : DR·Lucy S KingIan H Gotlib
May 6, 2021·The Journal of Genetic Psychology·Randi A BatesLaura M Justice
Jul 2, 2021·Biochimica Et Biophysica Acta. Molecular Basis of Disease·Lukas CervenyFrantisek Staud
Aug 20, 2021·Biochimica Et Biophysica Acta. Molecular Basis of Disease·Hannah E J YongPadma Murthi
Aug 24, 2021·Developmental Psychobiology·Randi A BatesProsper Ssekayombya
Sep 11, 2021·Journal of Vascular Surgery·Kakra HughesNeil J Sehgal
Nov 10, 2021·Community Mental Health Journal·Kyunghee Lee, Liangliang Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pediatric Rehabilitation
Raymond K Mulhern, Robert W Butler
Developmental Medicine and Child Neurology
S Yudkin, G Yudkin
© 2022 Meta ULC. All rights reserved