PMID: 6967106Jun 1, 1980Paper

Effects of previous activity on the energetics of activation in frog skeletal muscle

The Journal of General Physiology
J A Rall

Abstract

Effects of previous activity on the ability of frog skeletal muscle at 0 degrees C to liberate energy associated with contractile activation, i.e., activation heat (AH), have been examined. Earlier work suggests that activation heat amplitude (as measured from muscles stretched to lengths where active force development is nearly abolished) is related to the amount of Ca2+ released upon stimulation. After a twitch, greater than 2 s is required before a second stimulus (AHt) can liberate the same activation heat as a first stimulus (AH infinity), i.e., (AHt)/(AH infinity) = 1 -0.83 e-1.40t, where t is time in seconds. Caffeine introduces a time delay in the recovery of the ability to generate activation heat after a twitch. After a tetanus, the activation heat is depressed to a greater extent at any time than after a twitch. The activation heat elicited by a stimulus 1 s after a tetanus is depressed progressively with respect to tetanus duration up to 3 s. For tetani of 3, 40, and 80 s duration the postetanus activation heat is comparably depressed. The time-course of the recovery of the ability of the muscle to produce activation heat after a tetanus can be described as (AHt)/(AH infinity) = 1 -0.80 e-0.95t -0.20 e-0.02t. Greate...Continue Reading

References

Apr 21, 1975·Biochimica Et Biophysica Acta·G Meissner
Dec 22, 1977·Nature·G Suarez-Kurtz, I Parker

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Citations

Jan 1, 1991·European Journal of Applied Physiology and Occupational Physiology·A L HicksJ Dent
Oct 1, 1986·Pflügers Archiv : European journal of physiology·A de HaanH G Westra
Dec 1, 1984·Pharmacology, Biochemistry, and Behavior·C J Meliska, W H Loke
Apr 14, 2007·Statistics in Medicine·Nobutane Hanayama
Dec 12, 2013·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Barbara WilhelmHelmut Wilhelm
Aug 1, 1981·Journal of Clinical Pharmacology·S A Turkanis, R Karler
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Jul 15, 2016·The Journal of Physiological Sciences : JPS·Kazuhiro Yamada
Jul 28, 2019·Journal of Muscle Research and Cell Motility·C J Barclay, B S Launikonis
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Sep 1, 1990·The American Journal of Physiology·R L MooreM E Houston
May 1, 1982·The American Journal of Physiology·D M BurchfieldR G Rahwan
Nov 1, 1989·The American Journal of Physiology·B M Palmer, R L Moore

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