Effects of protein level, methionine supplementation and carbohydrate type of the diet on liver lipid and plasma free threonine contents in the lactating rat

Reproduction, Nutrition, Development
J LeclercJ Belleville

Abstract

Eight groups of 13-15 female rats were fed purified diets after littering. Four groups received a low protein (8% casein) diet (groups 8) and the others, a normal protein (20% casein) diet (groups 20). Carbohydrates were supplied either as starch (groups S) or as starch plus 40% fructose (groups F). Half the animals received a 0.4% methionine supplementation (groups M). Four or five dams per group were sacrificed on days 2, 7 and 14 after littering. The diet intake was increased by methionine supplementation, substitution of starch for fructose and increased protein content, mainly during the second week of lactation. This influenced weight variation of the dams and litter growth. On all days, the plasma levels of cholesterol esters, triglycerides and phospholipids were positively correlated with the dietary protein level. On days 7 and 14, the liver neutral lipid content was increased in rats fed the low protein diets supplemented with methionine (groups 8SM and 8FM) and the normal protein diets containing 40% fructose (groups 20F and 20FM). The plasma free threonine content was positively correlated with the protein level in the diet. On day 14, rats fed a low protein diet had a threonine deficiency, except those in groups 8S...Continue Reading

Citations

Aug 15, 2000·Journal of Chromatography. a·V Ruiz-Gutiérrez, M C Pérez-Camino
May 11, 2012·The British Journal of Nutrition·Panagiotis SakkasIlias Kyriazakis
Sep 16, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·L E P Wood
Dec 1, 1992·Diabetes/metabolism Reviews·K O'Dea

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