Effects of protein sources and levels in antibiotic-free diets on diarrhea, intestinal morphology, and expression of tight junctions in weaned piglets

Animal Nutrition
Yunpeng WuXianyong Ma

Abstract

This study examined effects of dietary protein sources and levels on intestinal health of 21 to 35 d-old weaned piglets fed antibiotics-free diets. A total of 150 weaned piglets (21 d of age) were allotted to 5 dietary treatment groups. Diets were formulated, based on corn-soybean meal, with different protein sources (fish meal and soy protein concentrate) to provide different dietary CP levels. Piglets within 5 dietary treatments were fed diets as follows, respectively: 1) control diet of 17% CP (control); 2) 19% CP diets formulated with more soy protein concentrate (SPC19); 3) fish meal (FM19); 4) 23.7% CP diets formulated with more soy protein concentrate (SPC23); 5) fish meal (FM23). The results showed that piglets from control group had higher ADG and lower incidence of diarrhea compared with those of other groups (P < 0.05). The incidence of diarrhea of piglets in FM19 group was lower than those from SPC23 group and FM23 group (P < 0.05). With the higher CP levels, villous height and villous height to crypt depth ratio of piglets in the duodenum and jejunum were decreased (P < 0.05), but crypt depth was increased (P < 0.05). Comparing control group and other groups, we found the expression of inflammatory cytokines interl...Continue Reading

Citations

Jun 23, 2020·Mediators of Inflammation·Jing GaoYuLong Yin
Dec 13, 2017·Journal of the Science of Food and Agriculture·Branko T PetrujkićDavid J Nisbet
Feb 22, 2021·Animal : an International Journal of Animal Bioscience·C LarsenC Amdi
Aug 8, 2021·Animals : an Open Access Journal From MDPI·Farhad M PanahTina Skau Nielsen
Feb 20, 2018·Journal of Agricultural and Food Chemistry·Xianyong MaYueqin Qiu
Nov 2, 2021·Journal of Animal Physiology and Animal Nutrition·Jiangying XiaJunliang Deng

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Methods Mentioned

BETA
electrophoresis
PCR

Software Mentioned

Primer premier
SAS

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