Effects of Pulmonary Rehabilitation on Exacerbation Number and Severity in People With COPD: An Historical Cohort Study Using Electronic Health Records

Chest
Elizabeth MooreJennifer K Quint

Abstract

In previous systematic reviews (predominantly of randomized controlled trials), pulmonary rehabilitation (PR) has been shown to reduce hospital admissions for acute exacerbations of COPD (AECOPD). However, findings have been less consistent for cohort studies. The goal of this study was to compare rates of hospitalized and general practice (GP)-treated AECOPD prior to and following PR. Using anonymized data from the Clinical Practice Research Datalink and Hospital Episode Statistics, hospital admissions and GP visits for AECOPD were compared 1 year prior to and 1 year following PR in patients referred for PR. Exacerbation rates were also compared between individuals eligible and referred for PR vs those eligible and not referred. A total of 69,089 (64%) of the patients with COPD in the cohort were eligible for PR. Of these, only 6,436 (9.3%) were recorded as having been referred for rehabilitation. A total of 62,019 (89.8%) were not referred, and 634 (0.98%) declined referral. When combining GP and hospital exacerbations, patients who were eligible and referred for PR had a slightly higher but not statistically significant exacerbation rate (2.83 exacerbations/patient-year; 95% CI, 2.66-3.00) than those who were eligible but no...Continue Reading

References

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Jul 19, 2016·Journal of Cardiopulmonary Rehabilitation and Prevention·Shawn P E NishiGulshan Sharma
Dec 7, 2016·Clinical Epidemiology·Kieran J RothnieJennifer K Quint

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Citations

Jun 21, 2018·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jose Luis Lopez-CamposEsther Barreiro
May 8, 2019·International Journal of Epidemiology·Catherine JohnMartin D Tobin
Jan 29, 2020·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Jane S WatsonSheila Greenfield
Nov 2, 2019·BMJ Open Respiratory Research·Keir PhilipNicholas S Hopkinson
Jun 17, 2020·Respirology : Official Journal of the Asian Pacific Society of Respirology·Amy H AttawaySrinivasan Dasarathy
Feb 16, 2021·ERJ Open Research·Philip W StoneSally J Singh
Nov 26, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Philip W StoneSally J Singh
Feb 23, 2021·Internal and Emergency Medicine·Kiki Waeijen-SmitFrits M E Franssen
Jul 22, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Jose Luis López-CamposCandelaria Caballero-Eraso
Jul 21, 2021·American Journal of Respiratory and Critical Care Medicine·Mihaela S StefanPeter K Lindenauer

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