Effects of qinghaosu and related compounds on incorporation of [G-3H] hypoxanthine by Plasmodium falciparum in vitro.

Transactions of the Royal Society of Tropical Medicine and Hygiene
Z L LiW Peters

Abstract

The effects of qinghaosu (QHS), dihydroqinghaosu (DHQ), artemether and alpha-propoxycarbonyl dihydroartemisine (SM242) on incorporation of [G-3H] hypoxanthine into Plasmodium falciparum were studied in vitro. Antimalarial activity in vitro is enhanced by reduction of the keto group, since DHQ, artemether and SM242 were more than 100 times more active than QHS.

References

Dec 1, 1979·Antimicrobial Agents and Chemotherapy·R E DesjardinsJ D Chulay
Aug 7, 1982·Lancet·J B JiangK Arnold
Feb 1, 1981·Annals of Tropical Medicine and Parasitology·J O OsisanyD C Warhurst
May 1, 1981·The British Journal of Psychiatry : the Journal of Mental Science·X Liu
Jan 1, 1981·The American Journal of Chinese Medicine·R M CoanP L Coan
Jan 1, 1981·The American Journal of Chinese Medicine·J O Sodipo, T A Ogunbiyi

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Citations

Dec 15, 1984·Experientia·W Peters
Oct 19, 1990·Pharmaceutisch Weekblad. Scientific Edition·H J WoerdenbagN Pras
May 1, 1996·International Journal for Parasitology·T S SkinnerT M Davis
Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·H M GuW Peters
Jan 1, 1986·Transactions of the Royal Society of Tropical Medicine and Hygiene·S WakiM Suzuki
Jan 1, 1986·Transactions of the Royal Society of Tropical Medicine and Hygiene·A N ChawiraW Peters
Jan 1, 1987·Transactions of the Royal Society of Tropical Medicine and Hygiene·S R Krungkrai, Y Yuthavong
Jan 1, 1987·Transactions of the Royal Society of Tropical Medicine and Hygiene·B C ElfordR J Wilson
Sep 1, 1990·Transactions of the Royal Society of Tropical Medicine and Hygiene·M H AlinM Ashton
Jul 1, 1992·Transactions of the Royal Society of Tropical Medicine and Hygiene·M Hassan AlinM Ashton
Jan 1, 1990·Pharmacology & Therapeutics·I S Lee, C D Hufford
Jan 1, 1996·Transactions of the Royal Society of Tropical Medicine and Hygiene·M Hassan AlinA Björkman
Sep 1, 1989·Antimicrobial Agents and Chemotherapy·S H Xiao, B A Catto
Oct 1, 1990·Antimicrobial Agents and Chemotherapy·O Y KeR L Berens
Apr 13, 2010·Molecular and Biochemical Parasitology·David A Baker
Jun 25, 2008·Drug Metabolism and Pharmacokinetics·Diem Thuy Le ThiKesara Na-Bangchang
Apr 1, 1985·Parasitology·R E Howells
Apr 1, 1985·Parasitology·W Peters
Oct 1, 1986·Annals of Tropical Medicine and Parasitology·W PetersD C Warhurst
Oct 1, 1987·Annals of Tropical Medicine and Parasitology·R E Howells
Sep 10, 1999·Phytotherapy Research : PTR·A El-TahirS A Khalid
May 1, 1997·Antimicrobial Agents and Chemotherapy·T K DienC J van Boxtel

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