Effects of quercetin on antioxidant potential in the experimental periodontitis development

Interventional Medicine & Applied Science
Andrii DemkovychPetro Hasiuk

Abstract

The results of experimental research of antioxidant system are presented in this article. Superoxide dismutase activity, catalase, and ceruloplasmin have been determined on the 7th and 14th days of experimental periodontitis development both without correction and with the injection of a water-soluble quercetin drug (corvitin). Hence, there was a decrease in superoxide dismutase activity, intensive increase in catalase activity, and ceruloplasmin maintenance in the blood serum during acute period of inflammatory process. The usage of flavonoid for 7  days resulted in stabilization of radical oxidation due to reduction of superoxide dismutase activity, maintenance at the high-level catalase activity, and ceruloplasmin concentration in the rat's blood plasma with experimental bacterial-immune periodontitis.

References

Oct 1, 1982·Canadian Journal of Physiology and Pharmacology·J A MoffatG S Marks
Mar 17, 2004·Free Radical Biology & Medicine·Robert J WilliamsCatherine Rice-Evans
Nov 19, 2011·Journal of Clinical Periodontology·Naofumi TamakiManabu Morita
Feb 9, 2012·Current Drug Delivery·Andreia AscensoSandra Simoes
Mar 5, 2015·The International Journal of Periodontics & Restorative Dentistry·Shilpa TrivediShivani Pandey
Sep 24, 2015·Fitoterapia·Gabriele D'Andrea
Jul 13, 2017·Postgraduate Medical Journal·Andrew Jacob GrossMartin S Lipsky
Jun 29, 2018·Interventional Medicine & Applied Science·Andrii DemkovychPetro Anatoliyovych Hasiuk

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