Effects of Race and Sex on Features of Eosinophilic Esophagitis

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Fouad J MoawadMirna Chehade

Abstract

Clinical and endoscopic features of eosinophilic esophagitis (EoE) differ between children and adults and among racial backgrounds. We investigated whether there were any associations between race or sex and clinical presentation, endoscopic features, and histologic findings from patients with EoE of various racial backgrounds. We performed a retrospective, multicenter, cross-sectional analysis of 793 patients with EoE (476 adults and 317 children; mean age, 26 years; range, 0.1-84 years; 72% male) from clinical registries at 5 tertiary care centers in the United States. EoE was defined per consensus guidelines. Data with predetermined variables were extracted from clinical registries at each participating institution. Of the study cohort, 660 patients were white (83%), 77 were African American (10%), and 56 were of other races (7%). A significantly larger proportion of white persons than African Americans or other races had dysphagia (74%, 56%, and 53%, respectively; P < .001), food impaction (35%, 13%, and 13%, respectively; P < .001), and features of EoE that included rings (46%, 25%, and 18%, respectively; P < .001) or furrows (70%, 58%, and 55%, respectively; P = .012). Males and females had similar clinical presentations,...Continue Reading

References

Aug 27, 2004·The New England Journal of Medicine·Richard J NoelMarc E Rothenberg
Dec 13, 2007·The Journal of Allergy and Clinical Immunology·Carine BlanchardMarc E Rothenberg
Jul 7, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ganapathy A PrasadNicholas J Talley
Nov 21, 2009·Alimentary Pharmacology & Therapeutics·F J MoawadR K H Wong
Sep 23, 2010·Gastroenterology·Monika A KwiatekJohn E Pandolfino
Oct 6, 2010·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Javier Molina-InfanteMaria Angeles Gonzalez-Nuñez
Oct 25, 2011·The Journal of Allergy and Clinical Immunology·Petr HruzUNKNOWN Swiss EoE study group
Feb 9, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Joohee LeeJeffrey A Alexander
Jun 26, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Evan S Dellon
Nov 28, 2013·Gastrointestinal Endoscopy·Evan S DellonNicholas J Shaheen
Dec 18, 2013·The Journal of Allergy and Clinical Immunology·Rupinder K GillSteven M Schwarz
Mar 8, 2014·Digestive Diseases·Petr Hruz
Mar 25, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Bram D van RhijnAlbert J Bredenoord
May 9, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Thomas WeilerHemant Sharma
Aug 26, 2014·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Daniel ChathamJay A Lieberman

❮ Previous
Next ❯

Citations

Apr 21, 2016·Digestive Diseases and Sciences·Dustin AlbertFouad J Moawad
Oct 8, 2016·Revista de gastroenterología de México·R Soto-SolísM A Ballesteros-Amozurrutia
Jun 6, 2017·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·N GonsalvesP J Bryce
Jun 12, 2017·The Journal of Allergy and Clinical Immunology·Elizabeth T JensenEvan S Dellon
Mar 30, 2018·Digestive Diseases and Sciences·Diego García-CompeánHéctor J Maldonado-Garza
Aug 15, 2017·Expert Review of Gastroenterology & Hepatology·Alfredo J LucendoLaura Arias-González
Jan 1, 2018·Clinical Reviews in Allergy & Immunology·Diana Muñoz-MendozaSami L Bahna
Oct 19, 2017·F1000Research·Sandy Durrani, Marc Rothenberg
Jan 27, 2018·Clinical Reviews in Allergy & Immunology·Emily Ko, Mirna Chehade
Aug 5, 2020·Expert Review of Gastroenterology & Hepatology·Ángel Arias, Alfredo J Lucendo
Jul 6, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Norihisa IshimuraShunji Ishihara
Feb 11, 2019·Journal of Clinical Psychology in Medical Settings·L Guadagnoli, T H Taft
Apr 5, 2018·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·N J ShaheenG W Falk
Jul 31, 2020·Expert Review of Clinical Immunology·Mirna Chehade, Shimron Brown
Nov 11, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Daniel CisternasJordi Serra
Apr 18, 2021·Immunology and Allergy Clinics of North America·Christopher M WarrenRuchi S Gupta
Apr 23, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ikuo HiranoUNKNOWN ORBIT1/SHP621-301 Investigators
May 19, 2021·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Mark MahonDaniela Levanon
Jul 16, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Elizabeth A ErwinOctavio Ramilo
Jul 10, 2021·The Journal of Allergy and Clinical Immunology·UNKNOWN COREOS Collaborators:Ekaterina Safroneeva
May 4, 2021·Journal of Pediatric Gastroenterology and Nutrition·Paroma BoseWilliam E Bennett
Nov 20, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Philipp SchreinerLuc Biedermann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.