Effects of reference electrode location on monopolar-derived multifocal electroretinograms in cynomolgus monkeys

Documenta Ophthalmologica. Advances in Ophthalmology
Charlene B Y KimT Michael Nork

Abstract

The purpose of this study is to determine the effect of reference electrode location on the multifocal electroretinographic waveform. Multifocal electroretinograms (mfERGs) were recorded from 20 ocularly normal cynomolgus monkeys. The corneal electrode was an ERG-jet referenced to an ipsilaterally (outer canthus) situated subdermal needle electrode and to the contralateral corneal electrode. Testing was monocular and recordings from both montages were obtained simultaneously. The stimulus array consisted of 103 equal-sized hexagonal elements, which subtended +/-44 degrees about the central visual axis. Mean luminance of the display was 100 cd/m2. First-order (K1) and second-order (first slice) kernels (K2.1) of the mfERG were grouped in (a) 4 rings, representing the central 56 degrees of visual field and (b) in 15-element quadrants. The mfERG waveform measures included amplitude, implicit time, and root mean square (RMS) of the oscillatory potentials (OP) and response waveform. K1 and K2.1 ring and quadrant amplitudes were larger with the contralateral than with the ipsilateral reference, but more notably signal-to-noise ratios (S:N) of the response waveform were always larger with the ipsilateral reference. Implicit times were...Continue Reading

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Jan 29, 2005·Documenta Ophthalmologica. Advances in Ophthalmology·Charlene B Y KimT Michael Nork

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Citations

Sep 14, 2011·Archives of Ophthalmology·T Michael NorkBrian J Christian
Apr 28, 2010·Documenta Ophthalmologica. Advances in Ophthalmology·T Michael NorkJames N Ver Hoeve
Dec 28, 2011·Documenta Ophthalmologica. Advances in Ophthalmology·Charlene B Y KimT Michael Nork
May 10, 2008·Documenta Ophthalmologica. Advances in Ophthalmology·Jonathan S Lyons, Matthew L Severns
Jun 15, 2007·Acta Ophthalmologica Scandinavica·Maria Voss KyhnMorten la Cour
Mar 6, 2007·American Journal of Ophthalmology·Jonathan S Lyons, Matthew L Severns
Aug 3, 2013·Korean Journal of Ophthalmology : KJO·Jee Wook KimKyung Seek Choi
Oct 20, 2006·Current Eye Research·Nathan A MaertzJames N Ver Hoeve

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