Abstract
Although language disorders occur in about 50% of patients with a left hemispheric tumour and are a significant cause of morbidity, the effects of resective neurosurgery and their relation to tumour pathology are unclear. We report the immediate effects of resective surgery on language functions in a heterogeneous group of patients with left-sided intracranial tumours. 40 patients were studied. The Western Aphasia Battery (WAB) and Boston Naming Test (BNT) were administered preoperatively and before discharge following resective neurosurgery. Dexamethasone dose at time of testing was recorded, as was time taken to complete the tests, and tumour neuropathology. 15 patients with normal aphasia quotients and language quotients before resective surgery all had normal quotients postoperatively. 25 who were dysphasic (ie, aphasia quotient <93.8) preoperatively showed significant postoperative improvements in both their mean aphasia quotient (from 81.8 to 89.1, p=0.004) and their mean language quotient (from 73.4 to 85.4, p=0.001), though 13 remained dysphasic. Two of the 25 dysphasic patients had their WAB scores lowered by tumour resection. The findings and postoperative changes in BNT scores were almost identical to the pattern of ...Continue Reading
References
Sep 1, 1975·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·G G Briggs, R D Nebes
Dec 1, 1991·The Australian and New Zealand Journal of Surgery·I R WhittleK Elshunnar
Jul 1, 1991·Journal of Neurosurgery·R C RostomilyE Lettich
Jun 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·C J VechtS Z Stefanko
Sep 1, 1989·Journal of Neurosurgery·G OjemannM Berger
May 1, 1988·Journal of Neurosurgery·P C BurgerP Kleihues
Jan 1, 1989·Neurology·L D RechtD A Drachman
Jul 1, 1987·Neurosurgery·I CiricM Mikhael
Sep 1, 1988·Neurology·C FadulJ B Posner
Jan 1, 1987·Journal of Neuro-oncology·D E WeissmanM D Abeloff
Apr 1, 1994·Neurosurgery·M M HaglundG A Ojemann
Jul 1, 1994·Neurosurgery·B P HermannL Clement
Apr 1, 1996·Neurosurgery·S S SkirbollH R Winn
Jun 1, 1997·Journal of Neurosurgery·A M ThomsonI R Whittle
Jul 1, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·A Z LatifI R Whittle
Feb 1, 1957·Journal of Neurology, Neurosurgery, and Psychiatry·D SIMPSON
Citations
Jun 21, 2005·Lancet Neurology·Patrick MitchellA David Mendelow
Nov 7, 2001·Acta Neurologica Scandinavica·J GbadamosiC Heesen
Jan 26, 2006·Neurologia Medico-chirurgica·Masanori KurimotoShunro Endo
Nov 15, 2015·Acta neurochirurgica·Djaina SatoerArnaud Vincent
Jun 3, 2008·Surgical Neurology·Tatsumi MaedaJun-Ichi Kuratsu
May 12, 2004·Lancet·Ian R WhittleDonald Collie
Jun 27, 2015·Journal of Neurosurgery·Stephen M WilsonEdward F Chang
Aug 6, 2011·British Journal of Neurosurgery·S KerriganI R Whittle
Nov 1, 2001·The Cochrane Database of Systematic Reviews·S E Metcalfe, R Grant
Sep 23, 2006·Acta neurochirurgica·K SakuradaT Kayama
May 15, 2009·Acta neurochirurgica·Jennifer L ScotlandIan R Whittle
Jun 7, 2019·The Cochrane Database of Systematic Reviews·Michael G HartRobin Grant
Nov 18, 2018·Journal of Neuro-oncology·Justin Choon Hwee NgNicolas Kon Kam King
Sep 28, 2017·Brain Sciences·Katie VeretennikoffGail Robinson
Oct 24, 2017·Aphasiology·Angelica McCarronStephen M Wilson
May 5, 2000·The Cochrane Database of Systematic Reviews·S E Metcalfe
Oct 23, 2020·Neurosurgical Review·Ling-Hao BuJin-Song Wu
Apr 1, 2021·Neuropsychology Review·Christos PapatzalasIlias Papathanasiou