Effects of sedation on echocardiographic variables of left atrial and left ventricular function in healthy cats

Journal of Feline Medicine and Surgery
Jessica L WardJ D Bonagura

Abstract

Although sedation is frequently used to facilitate patient compliance in feline echocardiography, the effects of sedative drugs on echocardiographic variables have been poorly documented. This study investigated the effects of two sedation protocols on echocardiographic indices in healthy cats, with special emphasis on the assessment of left atrial size and function, as well as left ventricular diastolic performance. Seven cats underwent echocardiography (transthoracic two-dimensional, spectral Doppler, color flow Doppler and tissue Doppler imaging) before and after sedation with both acepromazine (0.1 mg/kg IM) and butorphanol (0.25 mg/kg IM), or acepromazine (0.1 mg/kg IM), butorphanol (0.25 mg/kg IM) and ketamine (1.5 mg/kg IV). Heart rate increased significantly following acepromazine/butorphanol/ketamine (mean±SD of increase, 40±26 beats/min) and non-invasive systolic blood pressure decreased significantly following acepromazine/butorphanol (mean±SD of decrease, 12±19 mmHg). The majority of echocardiographic variables were not significantly different after sedation compared with baseline values. Both sedation protocols resulted in mildly decreased left ventricular end-diastolic dimension and mildly increased left ventricul...Continue Reading

References

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Citations

Jan 19, 2016·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Karsten E Schober, Valérie Chetboul
Jan 19, 2016·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Brian A Scansen, Kyla L Morgan
Jan 19, 2016·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·L Ferasin, T DeFrancesco
Feb 26, 2013·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Danielle N Smith, Karsten E Schober
Feb 15, 2014·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Kiira T RodriguezRobert T O'Brien
May 7, 2015·Journal of Feline Medicine and Surgery·Noemi RomagnoliMarco Baron Toaldo
Jan 10, 2017·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Young Shin JooKi-Wug Sung
Apr 3, 2015·Journal of Feline Medicine and Surgery·Elisa Bortolami, Emma J Love
Sep 23, 2014·Journal of Feline Medicine and Surgery·Thibault RibasRomain Pariaut
Feb 19, 2019·Journal of the American Animal Hospital Association·Boeun KimJunghee Yoon
Dec 1, 2018·Journal of Feline Medicine and Surgery·Ryan C FriesDavid J Schaeffer
Apr 4, 2020·Journal of Veterinary Internal Medicine·Virginia Luis FuentesJoshua A Stern
Mar 16, 2017·Journal of Veterinary Internal Medicine·L C VisserJ A Stern
Nov 27, 2020·Journal of Veterinary Internal Medicine·Samantha L KochieVedat Yildez
Oct 27, 2020·Journal of Feline Medicine and Surgery·Bradley T Simon, Paulo V Steagall
Aug 15, 2020·Veterinary Anaesthesia and Analgesia·Eleonora LazzariniAlessandra M Carotenuto
Oct 5, 2021·Journal of the American Animal Hospital Association·Meghan E AllenKatherine F Scollan

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Methods Mentioned

BETA
sedation

Software Mentioned

TomTec
GraphPad
Graph Pad Prism
SAS

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