Effects of short supramaximal exercise on hemorheology in sickle cell trait carriers

European Journal of Applied Physiology
Philippe ConnesOlivier Hue

Abstract

This study compared the hemorheological profile at rest and in response to a short supramaximal exercise test between sickle cell trait (SCT) carriers and a control group. Eight SCT carriers and eight control subjects performed a ramp exercise test on a cycle ergometer conducted to maximal oxygen uptake (VO2max). One week later, they performed a supramaximal exercise test consisting of pedaling for 1 min at 110% VO2max. Blood viscosity (eta(b)), plasma viscosity (eta(p)), hematocrit (Hct) and red blood cell (RBC) rigidity were assessed at rest, at the end of exercise and at the 15th, 30th and 60th min of recovery. Exercise increased eta(b), eta(p) and Hct above resting values in both groups and these parameters remained higher until the 15th or 30th min of recovery as compared to resting values. RBC rigidity was unchanged from baseline values in both groups during exercise and recovery. No difference was observed between the two groups for eta(p) and Hct but eta(b) and RBC rigidity were higher in the SCT carriers at every time point compared with the control group. The higher RBC rigidity and eta(b) found in SCT carriers at rest and in response to a brief supramaximal exercise might constitute a risk factor for microcirculatory...Continue Reading

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Citations

Nov 13, 2007·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Julien TripettePhilippe Connes
Oct 22, 2008·Sports Medicine·Philippe ConnesOlivier Hue
Jun 11, 2011·Clinics in Sports Medicine·E Randy Eichner
Oct 12, 2010·Thrombosis Research·Eric BeltanPhilippe Connes
Aug 30, 2008·Autonomic Neuroscience : Basic & Clinical·Mona HédrevillePhilippe Connes
May 9, 2009·Scandinavian Journal of Medicine & Science in Sports·O HueM-D Hardy-Dessources
Aug 7, 2013·Chronobiology International·Mor DiawJulien Tripette
Nov 17, 2009·American Journal of Physiology. Heart and Circulatory Physiology·Lucile VincentLaurent Messonnier
Jun 29, 2010·American Journal of Physiology. Heart and Circulatory Physiology·Julien TripettePhilippe Connes
Apr 13, 2011·Journal of Forensic Sciences·Jon R ThogmartinLisa M Flannagan
Dec 4, 2020·Journal of Applied Physiology·Laurent A MessonnierLéonard Féasson
Aug 11, 2018·Medicine and Science in Sports and Exercise·Angèle N MerletLaurent A Messonnier
Oct 12, 2021·European Journal of Applied Physiology·K ReminyS Antoine-Jonville

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