Effects of simulated oxidation on the in vitro wear and mechanical properties of irradiated and melted highly crosslinked UHMWPE

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Ebru OralOrhun K Muratoglu

Abstract

Radiation crosslinked ultrahigh molecular weight polyethylene (UHMWPE) have reduced the wear rate of the bearing surface in total joint arthroplasty and the incidence of peri-prosthetic bone loss due to wear particles. The oxidation potential afforded to the material by the trapped residual free radicals after irradiation was addressed in first generation crosslinked UHMWPEs by using thermal treatments such as annealing or melting after irradiation. Postirradiation melted crosslinked UHMWPE did not contain detectable free radicals at the time of implantation and was expected to be resistant against oxidation for the lifetime of the implants. Recent analyses of long-term retrievals showed it was possible for irradiated and melted UHMWPEs to oxidize in vivo but studies on the effects of oxidation on these materials have been limited. In this study, we determined the effects of in vitro aging on the wear and mechanical properties of irradiated and melted UHMWPE as a function of radiation dose and found that even small amount of oxidation (oxidation index of 0.1) can have detrimental effects on its mechanical properties. There was a gradual increase in the wear rate below an oxidation index of 1 and a drastic increase thereafter. T...Continue Reading

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Citations

Jul 9, 2013·Journal of the Mechanical Behavior of Biomedical Materials·D BaykalS M Kurtz
Nov 7, 2012·Journal of the Mechanical Behavior of Biomedical Materials·P Abhiram SirimamillaClare M Rimnac
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Jan 10, 2018·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ebru OralOrhun K Muratoglu
Dec 27, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ebru OralOrhun K Muratoglu
Oct 22, 2019·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Zhenduo LiuLilan Gao
Jun 18, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ebru OralOrhun K Muratoglu

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