Effects of smoking on cardiopulmonary baroreceptor activation and peripheral vascular resistance

European Journal of Clinical Investigation
E ArosioA Lechi

Abstract

We studied 16 healthy smokers and 16 nonsmokers acting as controls. We subjected smokers and nonsmokers to cardiopulmonary baroreceptor stimulation by studying forearm and common carotid haemodynamic and sympathovagal balance. Smokers repeated the tests after smoking one cigarette. Smokers and controls were subjected to passive elevation of the legs and the trunk in a horizontal position with pressure monitoring and measurement of the calibre and flow in the brachial and common carotid arteries using a colourDoppler ultrasound. We calculated forearm resistance and carotid wall tension. We also studied R-R variability, calculating the ratio between low frequency (LF) and high frequency (HF) R-R interval variability. During stimulation diastolic blood pressure values decreased in controls and in smokers at rest. After smoking one cigarette, smokers showed an increase in systolic and diastolic blood pressure as well as in the heart rate during stimulation. Humeral artery increased the calibre during stimulation in both groups; after cigarette smoking the calibre declined throughout the study phases. Forearm resistance decreased in both groups during stimulation at rest, but increased after cigarette smoking. The LF/HF ratio decrea...Continue Reading

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Citations

May 19, 2010·Biomarkers in Medicine·Martin UnverdorbenBernhard R Winkelmann
Feb 26, 2011·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Nicholas Sjoberg, David A Saint
Feb 6, 2017·Hellenic Journal of Cardiology : HJC = Hellēnikē Kardiologikē Epitheōrēsē·Edvar Pereira Nascimento JúniorRafael Pereira
Sep 27, 2007·European Journal of Clinical Nutrition·C I WrightR Draijer
Sep 25, 2010·Anesthesiology·Yu ShiDavid O Warner
Aug 12, 2020·The FEBS Journal·Andrea PorzionatoRaffaele De Caro
Aug 30, 2019·Journal of Clinical Medicine·Yongjae YooRoderick J Finlayson

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