Effects of socioeconomic status and treatment disparities in colorectal cancer survival

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Hoa LeJason A Zell

Abstract

Poor survival among colorectal cancer (CRC) cases has been associated with African-American race and low socioeconomic status (SES). However, it is not known whether the observed poor survival of African-American CRC cases is due to SES itself and/or treatment disparities. We set out to determine this using data from the large, population-based California Cancer Registry database. A case-only analysis of CRC was conducted including all age groups using California Cancer Registry data from 1994 to 2003, including descriptive analysis of relevant clinical variables, race, and SES. CRC-specific survival univariate analyses were conducted using the Kaplan-Meier method. Multivariate survival analyses were done using Cox proportional hazards ratios (HR). Incident cases of colon (90,273) and rectal (37,532) cancer were analyzed, including 91,739 (71.8%) non-Hispanic Whites, 8,535 (6.7%) African-Americans, 14,943 (11.7%) Hispanics, 3,564 (2.8%) Chinese, and 7,950 (6.2%) non-Chinese Asians. African-Americans had a greater proportion of metastatic stage at presentation (P < 0.0001) and decreased CRC-specific survival (P < 0.0001 for colon and rectal cancer). After adjustment for age, sex, histology, site within the colon, and stage, Afri...Continue Reading

References

Apr 1, 1991·American Journal of Public Health·C JepsonT Gibbs
Nov 15, 1995·Journal of the National Cancer Institute·R M MayberryM A Haynes
Aug 15, 1996·Cancer·J M JessupD P Winchester
Sep 1, 1996·Medical Care·J K Ball, A Elixhauser
Sep 1, 1999·Cancer Detection and Prevention·S E TropmanT Aldrich
Nov 15, 2000·American Journal of Public Health·R G RoetzheimJ P Krischer
Dec 21, 2000·JAMA : the Journal of the American Medical Association·D SchragC B Begg
Apr 12, 2001·Journal of Clinical Epidemiology·S Marcella, J E Miller
Sep 5, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D SchragC B Begg
May 2, 2002·Archives of Surgery·L James WudelSteven C Stain
Sep 19, 2002·Cancer Practice·Margaret Holmes-RovnerC William Given
Sep 28, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Deborah SchragColin B Begg
Jan 9, 2003·Cancer·Rangaswamy GovindarajanLaura F Hutchins
Mar 14, 2003·JAMA : the Journal of the American Medical Association·Judith M E Walsh, Jonathan P Terdiman
Mar 29, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·John Z AyanianWilliam E Wright
Apr 17, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Rosemary D CressSharon L Campleman
Feb 11, 2004·Archives of Surgery·Arden M MorrisLaura-Mae Baldwin
Feb 21, 2004·CA: a Cancer Journal for Clinicians·Robert A SmithUNKNOWN American Cancer Society
Mar 4, 2005·The American Journal of Gastroenterology·Sangeeta AgrawalUNKNOWN Committee of Minority Affairs and Cultural Diversity, American College of Gastroenterology
Aug 18, 2005·Journal of the National Cancer Institute·Laura-Mae BaldwinStephen H Taplin
Nov 17, 2005·Journal of the National Cancer Institute. Monographs·Sharon RolnickChristine C Johnson
Mar 28, 2006·Preventive Medicine·Randal H RobertsonNorman W Weissman
Apr 15, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kimberly IrbySusan S Devesa
May 10, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Blase N PoliteOlufunmilayo I Olopade
Jan 17, 2007·Medical Care·Kathryn A PhillipsStephanie L Van Bebber
Jan 24, 2007·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Mar 21, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jason A ZellHoda Anton-Culver
Oct 9, 2007·Journal of Community Health·Navkiran K ShokarSusan C Weller
Jan 1, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jason A ZellHoda Anton-Culver

❮ Previous
Next ❯

Citations

Jul 21, 2009·Diseases of the Colon and Rectum·Charlie M WrayJason A Zell
Apr 8, 2011·Diseases of the Colon and Rectum·Chuan-Ju G PanJason A Zell
Jan 9, 2013·Cancer Causes & Control : CCC·Kristin WallaceAnthony J Alberg
Jun 4, 2010·Digestive Diseases and Sciences·Kevin M GoreyMadhan K Balagurusamy
Nov 4, 2011·Journal of Community Health·Kushal PatelBill Blot
Jan 20, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Wendy LeeJoseph Kim
Jun 24, 2011·Journal of the National Cancer Institute·Daixin YinRobert R German
Jun 10, 2011·American Journal of Clinical Oncology·Charles B SimoneJames M Metz
Apr 20, 2012·Diseases of the Colon and Rectum·Hossein MasoomiJason A Zell
Nov 8, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jason A ZellHoda Anton-Culver
Oct 1, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Jason A ZellHoda Anton-Culver
Jan 22, 2013·Annals of Surgical Oncology·James R NitzkorskiElin R Sigurdson
Jun 19, 2013·Annals of Surgical Oncology·Uma R PhatakCurtis J Wray
Aug 13, 2009·World Journal of Gastroenterology : WJG·Anastasios DimouMuhammad Wasif Saif
Mar 6, 2013·Journal of Cancer·Terry Hyslop, Scott A Waldman
Feb 8, 2013·Biomarkers in Medicine·Terry Hyslop, Scott A Waldman
Dec 4, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Walter Y TsangJason A Zell
Jun 27, 2012·Biomarkers in Medicine·Jian P GongScott A Waldman
Jan 15, 2013·Journal of Immigrant and Minority Health·Abraham AragonesFrancesca M Gany
Feb 14, 2016·International Journal of Colorectal Disease·Bodil GesslerEva Angenete
Nov 6, 2013·Clinical Colorectal Cancer·Kristin WallaceAnthony J Alberg
Jul 31, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Helen M ShieldsSaul N Weingart
Jan 23, 2013·Gastrointestinal Endoscopy·Adeyinka O LaiyemoAmanda J Cross
Jul 14, 2010·International Journal of Radiation Oncology, Biology, Physics·Steve R MartinezRichard J Bold
Jun 24, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Mieke J AartsJan Willem W Coebergh
Sep 17, 2015·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Jan 19, 2012·Journal of Surgical Oncology·Terry HyslopScott A Waldman
Sep 19, 2012·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.