PMID: 108750Mar 29, 1979

Effects of sodium amylobarbitone on memory processes in the pigeon

Psychopharmacology
M HulmeS D Iversen

Abstract

An experiment was carried out in the pigeon to assess the effects of sodium amylobarbitone (SAB) on memory, using a delayed pair comparison task. Performance was disrupted at all delays by doses of 10 and 20 mg/kg SAB and it was concluded that this effect was not due to perceptual impairment or stereotyped responding, which the drug might have caused, since performance on a visual discrimination task was unaffected by the same doses of SAB. Two further experiments assessed proactive and retroactive effects by varying the inter-trial interval and by introducing an irrelevant orange stimulus at various stages of the delay interval. Although these manipulations disrupted performance, there was no evidence to suggest that the drug potentiated their effects in a specific manner. The results are discussed in terms of an encoding hypothesis, and some reference is made to the possible neuropharmacological basis of action of this drug.

References

Sep 15, 1978·Psychopharmacology·A Sahgal, S D Iversen
Feb 1, 1977·Journal of Comparative and Physiological Psychology·S T Mason, S D Iversen
Jul 1, 1977·Journal of the Experimental Analysis of Behavior·C P Shimp, M Moffitt
May 1, 1975·Journal of the Experimental Analysis of Behavior·D M Thompson
Aug 21, 1975·Psychopharmacologia·A Sahgal, S D Iversen
Jun 1, 1974·Journal of Comparative and Physiological Psychology·D Gaffan
Dec 1, 1965·Journal of Comparative and Physiological Psychology·R E Correll, W B Scoville
May 10, 1957·Science·R J HERRNSTEIN, W H MORSE
May 1, 1971·Journal of the Experimental Analysis of Behavior·M R D'Amato, W O'neill

Citations

Jan 1, 1980·Psychopharmacology·A SahgalS D Iversen
Jan 1, 1980·Psychopharmacology·A SahgalS D Iversen
Oct 1, 1994·Pharmacology, Biochemistry, and Behavior·K G WhiteJ E Watson
Jun 1, 1980·Behavioural Brain Research·A Sahgal, S D Iversen
Jan 1, 1984·Behavioural Brain Research·A Sahgal
Jan 1, 1981·Progress in Neuro-psychopharmacology·M D Morris, G F Gebhart
Jun 1, 1996·Brain Research. Cognitive Brain Research·A van Hest, T Steckler
Aug 1, 1988·IEEE Transactions on Bio-medical Engineering·V Annovazzi-Lodi, S Donati
Jun 1, 1985·British Journal of Clinical Pharmacology·P J CowenL E Braddock
Jul 1, 1980·British Journal of Clinical Pharmacology·E C Johnstone, I N Ferrier
Nov 1, 1986·Biological Psychiatry·A C AltamuraA Zanchetti

Related Concepts

Barbamyl
Metazoa
Color
Discrimination (Process of Differentiation)
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