PMID: 108750Mar 29, 1979

Effects of sodium amylobarbitone on memory processes in the pigeon

M HulmeS D Iversen


An experiment was carried out in the pigeon to assess the effects of sodium amylobarbitone (SAB) on memory, using a delayed pair comparison task. Performance was disrupted at all delays by doses of 10 and 20 mg/kg SAB and it was concluded that this effect was not due to perceptual impairment or stereotyped responding, which the drug might have caused, since performance on a visual discrimination task was unaffected by the same doses of SAB. Two further experiments assessed proactive and retroactive effects by varying the inter-trial interval and by introducing an irrelevant orange stimulus at various stages of the delay interval. Although these manipulations disrupted performance, there was no evidence to suggest that the drug potentiated their effects in a specific manner. The results are discussed in terms of an encoding hypothesis, and some reference is made to the possible neuropharmacological basis of action of this drug.


Sep 15, 1978·Psychopharmacology·A Sahgal, S D Iversen
Feb 1, 1977·Journal of Comparative and Physiological Psychology·S T Mason, S D Iversen
Jul 1, 1977·Journal of the Experimental Analysis of Behavior·C P Shimp, M Moffitt
May 1, 1975·Journal of the Experimental Analysis of Behavior·D M Thompson
Aug 21, 1975·Psychopharmacologia·A Sahgal, S D Iversen
Jun 1, 1974·Journal of Comparative and Physiological Psychology·D Gaffan
Dec 1, 1965·Journal of Comparative and Physiological Psychology·R E Correll, W B Scoville
May 10, 1957·Science·R J HERRNSTEIN, W H MORSE
May 1, 1971·Journal of the Experimental Analysis of Behavior·M R D'Amato, W O'neill


Jan 1, 1980·Psychopharmacology·A SahgalS D Iversen
Jan 1, 1980·Psychopharmacology·A SahgalS D Iversen
Oct 1, 1994·Pharmacology, Biochemistry, and Behavior·K G WhiteJ E Watson
Jun 1, 1980·Behavioural Brain Research·A Sahgal, S D Iversen
Jan 1, 1984·Behavioural Brain Research·A Sahgal
Jan 1, 1981·Progress in Neuro-psychopharmacology·M D Morris, G F Gebhart
Jun 1, 1996·Brain Research. Cognitive Brain Research·A van Hest, T Steckler
Aug 1, 1988·IEEE Transactions on Bio-medical Engineering·V Annovazzi-Lodi, S Donati
Jun 1, 1985·British Journal of Clinical Pharmacology·P J CowenL E Braddock
Jul 1, 1980·British Journal of Clinical Pharmacology·E C Johnstone, I N Ferrier
Nov 1, 1986·Biological Psychiatry·A C AltamuraA Zanchetti

Related Concepts

Discrimination (Process of Differentiation)
Columba livia
Reaction Time

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.